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J H Growdon

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Articles 203
Citations 7675
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Recent Articles
1.
Rieckmann A, Gomperts S, Johnson K, Growdon J, Van Dijk K
Neuroimage Clin . 2015 Jul; 8:554-9. PMID: 26137443
Prior work has shown that functional connectivity between the midbrain and putamen is altered in patients with impairments in the dopamine system. This study examines whether individual differences in midbrain-striatal...
2.
Ullman M, Corkin S, Coppola M, Hickok G, Growdon J, Koroshetz W, et al.
J Cogn Neurosci . 2013 Aug; 9(2):266-76. PMID: 23962016
Language comprises a lexicon for storing words and a grammar for generating rule-governed forms. Evidence is presented that the lexicon is part of a temporal-parietalhnedial-temporal "declarative memory" system and that...
3.
Gomperts S, Rentz D, Moran E, Becker J, Locascio J, Klunk W, et al.
Neurology . 2008 Sep; 71(12):903-10. PMID: 18794492
Background: Extrapyramidal motor symptoms precede dementia in Parkinson disease (PDD) by many years, whereas dementia occurs early in dementia with Lewy bodies (DLB). Despite this clinical distinction, the neuropsychological and...
4.
Tobin J, Latourelle J, Lew M, Klein C, Suchowersky O, Shill H, et al.
Neurology . 2008 May; 71(1):28-34. PMID: 18509094
Background: Microtubule-associated protein tau (MAPT) has been associated with several neurodegenerative disorders including forms of parkinsonism and Parkinson disease (PD). We evaluated the association of the MAPT region with PD...
5.
Salat D, Tuch D, van der Kouwe A, Greve D, Pappu V, Lee S, et al.
Neurobiol Aging . 2008 May; 31(2):244-56. PMID: 18455835
Prior work has demonstrated that the memory dysfunction of Alzheimer's disease (AD) is accompanied by marked cortical pathology in medial temporal lobe (MTL) gray matter. In contrast, changes in white...
6.
Irizarry M, Yao Y, Hyman B, Growdon J, Pratico D
Neurodegener Dis . 2007 Oct; 4(6):403-5. PMID: 17934322
Background: Oxidative damage is implicated in the pathophysiology of Alzheimer's disease (AD). F2-isoprostane is a marker of lipid peroxidation which is elevated in AD CSF. Plasma F2-isoprostane has been proposed...
7.
Lippa C, Duda J, Grossman M, Hurtig H, Aarsland D, Boeve B, et al.
Neurology . 2007 Mar; 68(11):812-9. PMID: 17353469
For more than a decade, researchers have refined criteria for the diagnosis of dementia with Lewy bodies (DLB) and at the same time have recognized that cognitive impairment and dementia...
8.
Wilk J, Tobin J, Suchowersky O, Shill H, Klein C, Wooten G, et al.
Neurology . 2006 Dec; 67(12):2206-10. PMID: 17190945
Background: Polymorphisms in the glutathione S-transferase pi gene (GSTP1), encoding GSTP1-1, a detoxification enzyme, may increase the risk of Parkinson disease (PD) with exposure to pesticides. Using the GenePD Study...
9.
Lleo A, Greenberg S, Growdon J
Annu Rev Med . 2006 Jan; 57:513-33. PMID: 16409164
Alzheimer's disease (AD) is an age-related neurodegenerative disease that affects approximately 4.5 million people in the United States. The mainstays of current pharmacotherapy for AD are compounds aimed at increasing...
10.
Gurol M, Irizarry M, Smith E, Raju S, Diaz-Arrastia R, Bottiglieri T, et al.
Neurology . 2006 Jan; 66(1):23-9. PMID: 16401840
Background: Microvascular brain injury, typically measured by extent of white matter hyperintensity (WMH) on MRI, is an important contributor to cognitive impairment in the elderly. Recent studies suggest a role...