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J G Moe

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Articles 17
Citations 308
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Recent Articles
1.
Davidowitz E, Lopez P, Patel D, Jimenez H, Wolin A, Eun J, et al.
J Neurochem . 2025 Mar; 169(3):e70025. PMID: 40052227
Targeting tau protein is a strategy for the development of disease-modifying therapeutics for Alzheimer's disease (AD) and numerous rare tauopathies. A small molecule approach targeting tau aggregation was used to...
2.
Fa M, Puzzo D, Piacentini R, Staniszewski A, Zhang H, Baltrons M, et al.
Sci Rep . 2016 Jan; 6:19393. PMID: 26786552
Non-fibrillar soluble oligomeric forms of amyloid-β peptide (oAβ) and tau proteins are likely to play a major role in Alzheimer's disease (AD). The prevailing hypothesis on the disease etiopathogenesis is...
3.
Kochakian C, Moe J
Fed Proc . 2010 Mar; 6(1 Pt 2):144. PMID: 20342732
No abstract available.
4.
Stone B, Cohen S, Breton G, Nietupski R, Pelletier D, Fiandaca M, et al.
Mol Cell Probes . 1996 Oct; 10(5):359-70. PMID: 8910891
Ribosomal RNA targets from Mycobacterium avium complex (23S), Mycoplasma pneumoniae (16S), Pneumocystis carinii (18S) and Legionella pneumophila (16S) were detected in four separate assays on a model automated Q-beta amplification...
5.
Moe J, Folta-Stogniew E, Russu I
Nucleic Acids Res . 1995 Jun; 23(11):1984-9. PMID: 7596827
Nuclear magnetic resonance spectroscopy has been used to characterize the kinetics and energetics of opening of base pairs in the DNA dodecamer [d(CGCAAATTTGCG)]2. The dodecamer contains an A3T3 tract that...
6.
Weisenseel J, Moe J, Reddy G, Marnett L, Stone M
Biochemistry . 1995 Jan; 34(1):50-64. PMID: 7819223
Structural refinement from solution 1H NMR data was performed on the 5'-d[ATCGC(PdG)-CGGCATG]-3'.5'-d[CATGCCGCGAT]-3' duplex, in which the adducted oligodeoxynucleotide containing the exocyclic lesion 1,N2-propano-2'-deoxyguanosine (PdG) was annealed with the complementary strand...
7.
Moe J, Reddy G, Marnett L, Stone M
Chem Res Toxicol . 1994 May; 7(3):319-28. PMID: 8075363
The exocyclic lesion 1,N2-propano-2'-deoxyguanosine (PdG) was incorporated into 5'-d[ATCGC(PdG)CGGCATG]-3', derived from the hisD3052 gene of Salmonella typhimurium. The modified oligodeoxynucleotide was annealed with the complementary strand 5'-d[CATGCCGCGAT]-3' which contained a...
8.
Singh U, Moe J, Reddy G, Weisenseel J, Marnett L, Stone M
Chem Res Toxicol . 1993 Nov; 6(6):825-36. PMID: 8117922
The exocyclic DNA adduct 1,N2-propano-2'-deoxyguanosine (PdG) was inserted into the oligodeoxynucleotide 5'-CGC(PdG)CGGCATG-3' and annealed to the complementary oligodeoxynucleotide 5'-CATGCCGCGCG-3'. This sequence is derived from a spontaneous revertant of the hisD3052...
9.
Moe J, Russu I
Biochemistry . 1992 Sep; 31(36):8421-8. PMID: 1327102
Proton nuclear magnetic resonance (NMR) spectroscopy is used to characterize the kinetics and energetics of base-pair opening in the dodecamers 5'-d(CGCGAATTCGCG)-3' and 5'-d(CGCGAATTTGCG)-3'. The latter dodecamer contains two symmetrical G.T...
10.
Moe J, Russu I
Nucleic Acids Res . 1990 Feb; 18(4):821-7. PMID: 2156233
We have used nuclear magnetic resonance (NMR) spectroscopy to measure the lifetimes of individual base-pairs in the palindromic DNA oligonucleotide 5'-d(CGCGAATTCGCG)-3' and in three other dodecamers with symmetrical base substitutions...