J G Hoenderop
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Explore the profile of J G Hoenderop including associated specialties, affiliations and a list of published articles.
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39
Citations
1755
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Recent Articles
1.
Dilmen E, Olde Hanhof C, Yousef Yengej F, Ammerlaan C, Rookmaaker M, Orhon I, et al.
Exp Cell Res
. 2024 Nov;
444(1):114342.
PMID: 39566879
Tubuloids are advanced in vitro models obtained from adult human or mouse kidney cells with great potential for modelling kidney function in health and disease. Here, we developed a polarized...
2.
Sendino Garvi E, van Slobbe G, Zaal E, de Baaij J, Hoenderop J, Masereeuw R, et al.
Stem Cell Res Ther
. 2024 Aug;
15(1):268.
PMID: 39183338
Background: The KCNJ16 gene has been associated with a novel kidney tubulopathy phenotype, viz. disturbed acid-base homeostasis, hypokalemia and altered renal salt transport. KCNJ16 encodes for Kir5.1, which together with...
3.
Olde Hanhof C, Dilmen E, Yousef Yengej F, Latta F, Ammerlaan C, Schreurs J, et al.
Front Cell Dev Biol
. 2023 Feb;
11:1086823.
PMID: 36760360
Kidney tubuloids are cell models that are derived from human or mouse renal epithelial cells and show high similarities with their counterparts. Tubuloids grow polarized in 3D, allow for long-term...
4.
Jansen J, Fedecostante M, Wilmer M, Peters J, Kreuser U, van den Broek P, et al.
Sci Rep
. 2016 Jun;
6:26715.
PMID: 27242131
The development of a biotechnological platform for the removal of waste products (e.g. uremic toxins), often bound to proteins in plasma, is a prerequisite to improve current treatment modalities for...
5.
Janssen D, Jansen C, Hafmans T, Verhaegh G, Hoenderop J, Heesakkers J, et al.
Acta Physiol (Oxf)
. 2016 Apr;
218(1):38-48.
PMID: 27124500
Aim: The molecular interactions between transient receptor potential vanilloid subtype 4 channels (TRPV4) and cell junction formation were investigated in the human and mouse urogenital tract. Materials And Methods: A...
6.
Jansen J, De Napoli I, Fedecostante M, Schophuizen C, Chevtchik N, Wilmer M, et al.
Sci Rep
. 2015 Nov;
5:16702.
PMID: 26567716
The bioartificial kidney (BAK) aims at improving dialysis by developing 'living membranes' for cells-aided removal of uremic metabolites. Here, unique human conditionally immortalized proximal tubule epithelial cell (ciPTEC) monolayers were...
7.
Jansen J, Fedecostante M, Wilmer M, van den Heuvel L, Hoenderop J, Masereeuw R
Biotechnol Adv
. 2014 Aug;
32(7):1317-1327.
PMID: 25135479
With the world-wide increase of patients with renal failure, the development of functional renal replacement therapies have gained significant interest and novel technologies are rapidly evolving. Currently used renal replacement...
8.
Jansen J, Schophuizen C, Wilmer M, Lahham S, Mutsaers H, Wetzels J, et al.
Exp Cell Res
. 2014 Feb;
323(1):87-99.
PMID: 24560744
Promising renal replacement therapies include the development of a bioartificial kidney using functional human kidney cell models. In this study, human conditionally immortalized proximal tubular epithelial cell (ciPTEC) lines originating...
9.
Martines A, Masereeuw R, Tjalsma H, Hoenderop J, Wetzels J, Swinkels D
Nat Rev Nephrol
. 2013 May;
9(7):385-98.
PMID: 23670084
In the past 8 years, there has been renewed interest in the role of iron in both acute kidney injury (AKI) and chronic kidney disease (CKD). In patients with kidney...
10.
Mutsaers H, Wilmer M, Reijnders D, Jansen J, van den Broek P, Forkink M, et al.
Biochim Biophys Acta
. 2012 Sep;
1832(1):142-50.
PMID: 23017367
During chronic kidney disease (CKD), drug metabolism is affected leading to changes in drug disposition. Furthermore, there is a progressive accumulation of uremic retention solutes due to impaired renal clearance....