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J F Ash

Explore the profile of J F Ash including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 1148
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Recent Articles
1.
Bornstein P, Ash J, Duksin D
Ups J Med Sci . 2010 Jan; 82(2):102. PMID: 20078299
No abstract available.
2.
Igo Jr R, Ash J
Somat Cell Mol Genet . 2000 Apr; 24(6):341-52. PMID: 10763412
Glutathione synthesis, a vital cellular process, depends on L-cystine uptake by the amino acid transporter, System x-C. Here we show that a second transporter, System X-AG, is required for normal...
3.
Levy L, Attwell D, Hoover F, Ash J, Bjoras M, Danbolt N
FEBS Lett . 1998 Mar; 422(3):339-42. PMID: 9498811
Inducible expression of the mammalian glial cell glutamate transporter GLT-1 has been established in a CHO cell line selected for low endogenous Na+-dependent glutamate uptake by [3H]aspartate suicide selection. Culturing...
4.
Tong X, Ash J, Caldwell K
J Membr Biol . 1997 Mar; 156(2):131-9. PMID: 9075644
Two Chinese hamster ovary cell (CHO-K1) mutants selected for defective glutamate transport via system X-AG are also highly permeable to small neutral molecules. Light microscopy demonstrated that exposure of one...
5.
Igo Jr R, Ash J
Somat Cell Mol Genet . 1996 Mar; 22(2):87-103. PMID: 8782489
Two new Chinese hamster ovary cell (CHO-K1) mutants lacking amino acid transport System X-AG activity were isolated by [3H]aspartate suicide selection. These null mutants, Dd-B6 and Dd-B7, were analyzed by...
6.
Igo Jr R, Ash J
Biochim Biophys Acta . 1995 Feb; 1233(2):153-62. PMID: 7865540
Pathways of L-glutamate and L-aspartate import by HeLa S3 cells were investigated before and after the cells were depleted of internal amino acids by starvation. Two new regulations of transport...
7.
DeBusk W, Ash J
Somat Cell Mol Genet . 1993 Jul; 19(4):331-45. PMID: 8211377
High levels of L-lysine were used to select for resistant variants of Chinese hamster ovary (CHO-K1) cells. Surviving colonies were screened for altered lysine transport and two with reduced uptake...
8.
Ash J, Igo Jr R
Biochim Biophys Acta . 1993 Jun; 1149(1):109-18. PMID: 8100448
The uptake of radiolabeled glutamate into cultured human (HeLa S3) and hamster (CHO-K1) cells was analyzed according to modified Michaelis-Menten models fit by the Marquardt least-squares method. Kinetic parameters not...
9.
Ash J, Igo Jr R, Morgan M, Grey A
Somat Cell Mol Genet . 1993 May; 19(3):231-43. PMID: 8101392
Transport of L-[3H]glutamate into Chinese hamster ovary cells (CHO-K1) was characterized and the results used to design a tritium suicide selection for cells with transport defects. Replicas of surviving colonies...
10.
Pauw P, Sheck R, Ash J
Mol Cell Biol . 1989 Jan; 9(1):116-23. PMID: 2538714
Measurements of internal ion concentrations, amino acid pools, and membrane potential were made across a series of HeLa subclones which are amplified for the genes for the sodium- and potassium-activated...