J E Saffitz
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Explore the profile of J E Saffitz including associated specialties, affiliations and a list of published articles.
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Articles
167
Citations
3791
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Recent Articles
1.
Saffitz J
Cardiovasc Pathol
. 2015 May;
3(2):87-91.
PMID: 25990853
Spontaneous ventricular tachyarrhythmias causing sudden death occur often in patients with healed myocardial infarcts. A reentrant mechanism has been implicated that depends, in part, on slow heterogeneous conduction and block...
2.
Saffitz J, Hoyt R, Luke R, Lee Kanter H, Beyer E
Trends Cardiovasc Med
. 2011 Jan;
2(2):56-60.
PMID: 21239275
Slow conduction leading to reentrant ventricular tachycardias in patients with healed myocardial infarcts appears to depend primarily on alterations in intercellular coupling at gap junctions of myocytes bordering the infarct...
3.
Sundset R, Ytrehus K, Zhang Y, Saffitz J, Yamada K
Cell Commun Adhes
. 2007 Dec;
14(5):239-49.
PMID: 18163233
Ischemic preconditioning increases the heart's tolerance to a subsequent longer ischemic period. The aim of this study was to investigate the effect of early and delayed preconditioning on gap junction...
4.
Kanno S, Saffitz J
Cardiovasc Pathol
. 2001 Oct;
10(4):169-77.
PMID: 11600334
Electrical activation of the heart requires cell-cell transfer of current via gap junctions, arrays of densely packed protein channels that permit intercellular passage of ions and small molecules. Because current...
5.
Eloff B, Lerner D, Yamada K, Schuessler R, Saffitz J, Rosenbaum D
Cardiovasc Res
. 2001 Sep;
51(4):681-90.
PMID: 11530101
Unlabelled: Analysis of mice with genetically altered expression of cardiac connexins can provide insights into the role of individual gap junction channel proteins in cell-to-cell communication, impulse propagation, and arrhythmias....
6.
Lerner D, Beardslee M, Saffitz J
Cardiovasc Res
. 2001 May;
50(2):263-9.
PMID: 11334830
No abstract available.
7.
Chiu H, Kovacs A, Ford D, Hsu F, Garcia R, Herrero P, et al.
J Clin Invest
. 2001 Apr;
107(7):813-22.
PMID: 11285300
Inherited and acquired cardiomyopathies are associated with marked intracellular lipid accumulation in the heart. To test the hypothesis that mismatch between myocardial fatty acid uptake and utilization leads to the...
8.
Wu J, Schuessler R, Rodefeld M, Saffitz J, BOINEAU J
Am J Physiol Heart Circ Physiol
. 2001 Feb;
280(3):H1232-40.
PMID: 11179068
This study reports the comparative quantitative, morphological, and electrophysiological properties of two pacemaker cell types, spider and spindle-shaped cells, isolated from the rabbit sinoatrial node. Isolated nodal cells were studied...
9.
Lerner D, Chapman Q, Green K, Saffitz J
J Heart Lung Transplant
. 2001 Feb;
20(1):93-7.
PMID: 11166617
We tested the hypothesis that cardiac allograft dysfunction in acute cardiac rejection may be related, in part, to diminished expression of connexin43, a gap junction channel protein that facilitates intercellular...
10.