J E Paciga
Overview
Explore the profile of J E Paciga including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
456
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Recent Articles
1.
Sun M, Paciga J, Feldman R, Yuan Z, Coppola D, Lu Y, et al.
Cancer Res
. 2001 Aug;
61(16):5985-91.
PMID: 11507039
We have shown previously that the AKT2 pathway is essential for cell survival and important in malignant transformation. In this study, we demonstrate elevated kinase levels of AKT2 and phosphatidylinositol-3-OH...
2.
Sun M, Wang G, Paciga J, Feldman R, Yuan Z, Ma X, et al.
Am J Pathol
. 2001 Aug;
159(2):431-7.
PMID: 11485901
Extensive studies have demonstrated that the Akt/AKT1 pathway is essential for cell survival and inhibition of apoptosis; however, alterations of Akt/AKT1 in human primary tumors have not been well documented....
3.
Burdick J, Chung E, Tanner G, Sun M, Paciga J, Cheng J, et al.
N Engl J Med
. 2000 Dec;
343(23):1697-701.
PMID: 11106719
No abstract available.
4.
Patton G, Paciga J, Shelley S
Toxicol Appl Pharmacol
. 1997 Nov;
147(1):126-34.
PMID: 9356315
Breathing air exposes humans and other mammals to various toxic agents including oxidative contaminants associated with fine particles of less than 2.5 micron which may be deposited in the deep...
5.
Shelley S, Paciga J, BALIS J
Biochim Biophys Acta
. 1991 Jun;
1096(4):338-44.
PMID: 2065105
Exposure of rats to 3 ppm ozone for up to 8 h results in significant changes in lamellar bodies, the surfactant storing organelles of type II cells. We have previously...
6.
Margraf L, Paciga J, BALIS J
Hum Pathol
. 1990 Apr;
21(4):392-6.
PMID: 2318480
Surfactant-associated (SA) glycoproteins are lung-specific proteins produced in the human lung by alveolar type II cells and Clara cells. The distribution of these proteins was studied immunohistochemically in lung tissue...
7.
Shelley S, Paciga J, PATERSON J, BALIS J
Lipids
. 1989 Sep;
24(9):769-74.
PMID: 2531262
Alveolar Type II cells in the rat respond to severe, acute ozone injury (3 ppm ozone for eight hours) by increasing their intracellular pool of surfactant; however, the newly stored...
8.
Wilbur D, Paciga J, Shelley S, Kanarek K, Cohen G, BALIS J
Pediatr Pulmonol
. 1989 Jan;
6(2):109-12.
PMID: 2927968
The prenatal relationships between surfactant disaturated phosphatidylcholine (DSPC) and surfactant-associated proteins of preterm infants with respiratory distress syndrome (RDS) have not been well documented. In the present study we measured...
9.
Paciga J, Shelley S, Paterson J, Knuppel R, Scerbo J, BALIS J
Ann Clin Lab Sci
. 1988 Mar;
18(2):141-7.
PMID: 3382157
Dot immunobinding assays for the quantitation of two classes of proteins associated with lung surfactant phospholipids in human amniotic fluid are described. With the use of these assays it was...
10.
BALIS J, PATERSON J, Paciga J, Haller E, Shelley S
Lab Invest
. 1985 Jun;
52(6):657-69.
PMID: 3892157
Human surfactant contains lung-specific, high molecular weight glycoproteins which are composed of disulfide-linked 34-kilodalton peptide subunits. We prepared antibodies to both isolated HMW glycoproteins and 34-kilodalton peptides and tested the...