J E Hale
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Explore the profile of J E Hale including associated specialties, affiliations and a list of published articles.
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70
Citations
615
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Recent Articles
11.
Funk J, Hale J, Carmines D, Gooch H, Hurwitz S
J Orthop Res
. 2000 Mar;
18(1):126-32.
PMID: 10716288
Diabetes mellitus has been shown to alter the properties of bone and impair fracture healing in both humans and animals. The objective of this study was to document changes in...
12.
Li W, Butler J, Hale J, McClure D, Little S, Czilli D, et al.
Neuroscience
. 2000 Jan;
95(1):1-4.
PMID: 10619456
Secreted isoforms of the beta-amyloid precursor protein potently enhance neuronal survival in cell cultures exposed to toxic amyloid beta peptide. Lowering of intracellular calcium levels to offset the increases in...
13.
An J, Zhao G, Churgay L, Osborne J, Hale J, Becker G, et al.
Am J Physiol
. 1999 Nov;
277(5):E862-9.
PMID: 10567013
Treatment of the pancreatic beta-cell line betaTC6-F7 with an imidazoline compound, RX-871024, KCl, or tolbutamide resulted in increased threonine phosphorylation of a 220-kDa protein (p220) concurrent with enhanced insulin secretion,...
14.
15.
Hall G, Crandall J, Carmines D, Hale J
J Biomech
. 1999 Mar;
32(2):203-7.
PMID: 10052928
The effect of loading rate on specimen calibration was investigated for an implantable force sensor of the two-point loading variety. This variety of sensor incorporates a strain gage to measure...
16.
Calder F, Jadhav V, Hale J
J R Coll Surg Edinb
. 1998 Apr;
43(1):17-9.
PMID: 9560500
Following the introduction of a dedicated 24-hour emergency theatre facility in a 500-bed district general hospital, the total amount of emergency general surgery performed after 22.00 hours has been reduced...
17.
Landt M, Gingerich R, Havel P, Mueller W, Schoner B, Hale J, et al.
Clin Chem
. 1998 Mar;
44(3):565-70.
PMID: 9510863
Adipose tissue secretes leptin, which interacts with receptors in the hypothalamus. In rodent models of obesity, leptin increases metabolism and decreases food intake, which helps to maintain normal body composition....
18.
Wang Q, Johnson R, Cox G, Villarreal E, Churgay L, Hale J
J Virol
. 1998 Jan;
72(2):1683-7.
PMID: 9445078
Reported here is the production of recombinant human rhinovirus 14 (HRV14) 2A protease from bacterial cells transformed with a heat-inducible plasmid containing the HRV14 2A cDNA sequence. Overexpressed 2A protein...
19.
Ill C, Gonzales J, Houtz E, Ludwig J, Melcher E, Hale J, et al.
Protein Eng
. 1997 Aug;
10(8):949-57.
PMID: 9415445
The complementarity-determining regions (CDRs) of a human kappa light chain were replaced with CDRs from a murine gamma-1 heavy chain and, by use of molecular modeling, key heavy chain framework...
20.
Zhang F, Basinski M, Beals J, Briggs S, Churgay L, CLAWSON D, et al.
Nature
. 1997 May;
387(6629):206-9.
PMID: 9144295
Mutations in the obese gene (OB) or in the gene encoding the OB receptor(OB-R) result in obesity, infertility and diabetes in a variety of mouse phenotypes. The demonstration that OB...