J E Gumperz
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Explore the profile of J E Gumperz including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
956
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Recent Articles
11.
Barber L, Percival L, Valiante N, Chen L, Lee C, Gumperz J, et al.
J Exp Med
. 1996 Aug;
184(2):735-40.
PMID: 8760827
The vast majority of new human HLA class I alleles are formed by conversions between existing alleles of the same locus. A notable exception to this rule is HLA-B*4601 formed...
12.
Barber L, Patel T, Percival L, Gumperz J, Lanier L, Phillips J, et al.
J Immunol
. 1996 May;
156(9):3275-84.
PMID: 8617950
MHC class I glycoproteins possess an invariant site for N-linked oligosaccharide addition at position 86 of the heavy chain. For human HLA-A, -B, and -C class I glycoproteins, position 86...
13.
Gumperz J, Valiante N, Parham P, Lanier L, Tyan D
J Exp Med
. 1996 Apr;
183(4):1817-27.
PMID: 8666938
Natural killer (NK) cells that express the NKB1 receptor are inhibited from killing target cells that possess human histocompatibility leukocyte antigen (HLA) B molecules bearing the Bw4 serological epitope. To...
14.
Gumperz J, Parham P
Nature
. 1995 Nov;
378(6554):245-8.
PMID: 7477341
Natural killer (NK) cells are controlled by receptors specific for polymorphic determinants of class I molecules of the major histocompatibility complex (MHC). The contrasting properties of NK and cytotoxic T...
15.
Arnett K, Adams E, Gumperz J, Darke C, Marsh S, Gelsthorpe K, et al.
Tissue Antigens
. 1995 Oct;
46(4):316-21.
PMID: 8560451
The primary structure of a variant HLA-B8 antigen has been determined by cDNA cloning and sequencing. The variant, B*0802 differs, from the common B*0801 subtype at positions 77-83 of the...
16.
Phillips J, Gumperz J, Parham P, Lanier L
Science
. 1995 Apr;
268(5209):403-5.
PMID: 7716542
Bacterial superantigens bind with high affinity to major histocompatibility complex (MHC) class II antigens on antigen-presenting cells and with T cell antigen receptor (TCR) beta chains on T lymphocytes, which...
17.
Lanier L, Gumperz J, Parham P, Melero I, Lopez-Botet M, Phillips J
J Immunol
. 1995 Apr;
154(7):3320-7.
PMID: 7897214
NK cells lyse hematopoietic cells that lack expression of MHC class I molecules on the cell surface. Transfection of certain MHC class I negative cell lines with MHC class I...
18.
Gumperz J, Litwin V, Phillips J, Lanier L, Parham P
J Exp Med
. 1995 Mar;
181(3):1133-44.
PMID: 7532677
Although inhibition of natural killer (NK) cell-mediated lysis by the class I HLA molecules of target cells is an established phenomenon, knowledge of the features of class I molecules which...
19.
Zemmour J, Gumperz J, Hildebrand W, Ward F, Marsh S, Williams R, et al.
Tissue Antigens
. 1992 May;
39(5):249-57.
PMID: 1384166
HLA haplotypes containing the HLA-B46 allele react with both anti-Cw1 and anti-Cw3 alloantisera, a pattern of reactivity defined as the Cw11 antigen and postulated to involve either a distinctive Cw11...