J E Gern
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Explore the profile of J E Gern including associated specialties, affiliations and a list of published articles.
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54
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1798
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Recent Articles
11.
Bizzintino J, Lee W, Laing I, Vang F, Pappas T, Zhang G, et al.
Eur Respir J
. 2010 Aug;
37(5):1037-42.
PMID: 20693244
A new and potentially more pathogenic group of human rhinovirus (HRV), group C (HRVC), has recently been discovered. We hypothesised that HRVC would be present in children with acute asthma...
12.
Korpi-Steiner N, Valkenaar S, Bates M, Evans M, Gern J, Bertics P
Clin Exp Allergy
. 2010 Jun;
40(8):1203-13.
PMID: 20545701
Background: Human rhinovirus (HRV) infections are a major cause of exacerbations in chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease, but HRV-induced immune responses of the lower...
13.
Bochkov Y, Hanson K, Keles S, Brockman-Schneider R, Jarjour N, Gern J
Mucosal Immunol
. 2009 Aug;
3(1):69-80.
PMID: 19710636
Rhinovirus (RV) infections trigger asthma exacerbations. Genome-wide expression analysis of RV1A-infected primary bronchial epithelial cells from normal and asthmatic donors was performed to determine whether asthma is associated with a...
14.
Bufford J, Reardon C, Li Z, Roberg K, DaSilva D, Eggleston P, et al.
Clin Exp Allergy
. 2008 Aug;
38(10):1635-43.
PMID: 18702654
Background: Exposure to pets in childhood has been associated with a reduced risk of wheezing and atopy. Objective: Our objective was to determine whether the effects of pet exposure on...
15.
Jartti T, Lee W, Pappas T, Evans M, Lemanske Jr R, Gern J
Eur Respir J
. 2008 May;
32(2):314-20.
PMID: 18448489
To better understand the viral aetiology of recurrent and prolonged illnesses, nasal secretions were prospectively collected from 285 infants at increased risk of developing asthma. Of these, 27 infants had...
16.
Sullivan Dillie K, Tisler C, Dasilva D, Pappas T, Roberg K, Carlson-Dakes K, et al.
Clin Exp Allergy
. 2007 Dec;
38(2):298-304.
PMID: 18070154
Rationale: Several studies have evaluated the associations between cord blood cellular responses and atopic diseases in children, but the results of these studies are inconsistent. Variations in blood processing factors...
17.
Gern J, Stone C, Nakano M, Muchmore D, de la Pena A, Park S, et al.
Clin Pharmacol Ther
. 2007 Jul;
83(2):307-11.
PMID: 17625517
The suitability of employing AIR Inhaled Insulin (AIR Insulin; AIR is a registered trademark of Alkermes) during acute upper respiratory tract infection (URI) has not been determined. Twenty-one healthy, non-diabetic...
18.
Amineva S, Mosser A, Binder J, Aminev A, Palmenberg A, Gern J
Arch Virol
. 2006 May;
151(10):1933-46.
PMID: 16732496
Interferons induced by viral infections can have powerful immuno- modulatory effects, and several epidemiologic studies have found an association between certain viral infections and reduced prevalence of allergy. We hypothesized...
19.
Amineva S, Aminev A, Palmenberg A, Gern J
J Gen Virol
. 2004 Sep;
85(Pt 10):2969-2979.
PMID: 15448360
Human rhinovirus (HRV) 3C protease (3Cpro) plays several important roles in the virus replication cycle. This enzyme cleaves the viral polyprotein at discrete sites to produce mature viral proteins and...
20.
Gern J, Vrtis R, Grindle K, Swenson C, Busse W
Am J Respir Crit Care Med
. 2000 Dec;
162(6):2226-31.
PMID: 11112143
To test the hypothesis that rhinovirus (RV)-induced immune responses influence the outcome of RV infections, we inoculated 22 subjects with allergic rhinitis or asthma with RV16. Nasal secretions and induced...