J E Gern
Overview
Explore the profile of J E Gern including associated specialties, affiliations and a list of published articles.
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54
Citations
1798
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Recent Articles
1.
Brown K, Krouse R, Calatroni A, Visness C, Sivaprasad U, Kercsmar C, et al.
PLoS One
. 2017 Jul;
12(7):e0180778.
PMID: 28686637
African Americans have higher rates of asthma prevalence, morbidity, and mortality in comparison with other racial groups. We sought to characterize endotypes of childhood asthma severity in African American patients...
2.
Liu Y, Rajamanikham V, Baron M, Patel S, Mathur S, Schwantes E, et al.
Clin Exp Allergy
. 2017 Feb;
47(3):371-382.
PMID: 28192616
Background: Children with risk alleles at the 17q21 genetic locus who wheeze during rhinovirus illnesses have a greatly increased likelihood of developing childhood asthma. In mice, overexpression of the 17q21...
3.
Loisel D, Du G, Ahluwalia T, Tisler C, Evans M, Myers R, et al.
Clin Exp Allergy
. 2015 Sep;
46(1):112-24.
PMID: 26399222
Background: Viral respiratory infections can cause acute wheezing illnesses in children and exacerbations of asthma. Objective: We sought to identify variation in genes with known antiviral and pro-inflammatory functions to...
4.
Gern J
Clin Exp Allergy
. 2014 Oct;
45(1):32-42.
PMID: 25270551
Rhinovirus (RV) infections are closely linked to exacerbations of asthma, and yet most RV infections of patients with asthma cause only upper respiratory symptoms. These findings suggest that RV and...
5.
Manthei D, Schwantes E, Mathur S, Guadarrama A, Kelly E, Gern J, et al.
Clin Exp Allergy
. 2014 Aug;
44(12):1484-93.
PMID: 25109477
Background: Asthma exacerbations contribute to significant morbidity, mortality and healthcare utilization. Furthermore, viral infections are associated with asthma exacerbations by mechanisms that are not fully understood. Objective: The aim of...
6.
Schwantes E, Manthei D, Denlinger L, Evans M, Gern J, Jarjour N, et al.
Clin Exp Allergy
. 2014 Jan;
44(6):813-21.
PMID: 24450586
Background: The majority of asthma exacerbations are related to viral respiratory infections. Some, but not all, previous studies have reported that low interferon responses in patients with asthma increase the...
7.
Demehri S, Yockey L, Visness C, Jaffee K, Turkoz A, Wood R, et al.
Clin Exp Allergy
. 2014 Jan;
44(6):851-7.
PMID: 24397611
Background: Mouse models of atopic march suggest that systemic, skin-derived thymic stromal lymphopoietin (TSLP) mediates progression from eczema to asthma. Objective: We investigated whether circulating TSLP is associated with eczema,...
8.
Stoltz D, Jackson D, Evans M, Gangnon R, Tisler C, Gern J, et al.
Clin Exp Allergy
. 2013 Jan;
43(2):233-41.
PMID: 23331564
Background: Specific patterns of allergic sensitization as well as quantification of the in vitro IgE response in early life may provide relevant clinical insight into future rhinitis and asthma risk....
9.
McLoughlin R, Calatroni A, Visness C, Wallace P, Cruikshank W, Tuzova M, et al.
Clin Exp Allergy
. 2011 Nov;
42(3):392-404.
PMID: 22092655
Background: Immunomodulatory T cells are thought to influence development of allergy and asthma, but early life longitudinal data on their phenotype and function are lacking. Objectives: As part of the...
10.
Amineva S, Aminev A, Gern J, Palmenberg A
J Gen Virol
. 2011 Jul;
92(Pt 11):2549-2557.
PMID: 21752966
HeLa cells are used to study the life cycles of many different viruses, including the human rhinoviruses (HRV) in the family Picornaviridae. Although the natural targets of HRV are human...