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J E French

Explore the profile of J E French including associated specialties, affiliations and a list of published articles. Areas
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Articles 99
Citations 754
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Recent Articles
1.
French J, Matson R, Thomason J, Wright T, Osborne V
J Dairy Sci . 2023 Mar; 106(5):3477-3492. PMID: 36935242
In the context of understanding lameness and injury from slipping, our objective was to characterize hoof impact and slide of 5 cows walking on 6 flooring surfaces commonly used in...
2.
Storer R, French J, Donehower L, Gulezian D, Mitsumori K, Recio L, et al.
Mutat Res . 2003 Oct; 540(2):165-76. PMID: 14550500
Genetically altered mouse models (GAMM) for human cancers have been critical to the investigation and characterization of oncogene and tumor suppressor gene expression and function and the associated cancer phenotype....
3.
McLaurin J, Cecal R, Kierstead M, Tian X, Phinney A, Manea M, et al.
Nat Med . 2002 Oct; 8(11):1263-9. PMID: 12379850
Immunization of transgenic mouse models of Alzheimer disease using amyloid-beta peptide (Abeta) reduces both the Alzheimer disease-like neuropathology and the spatial memory impairments of these mice. However, a therapeutic trial...
4.
Storer R, French J, Haseman J, Hajian G, LeGrand E, Long G, et al.
Toxicol Pathol . 2001 Nov; 29 Suppl:30-50. PMID: 11695560
The performance of the p53-/- transgenic (knockout) mouse model was evaluated through review of the data from 31 short-term carcinogenicity studies with 21 compounds tested as part of the International...
5.
Venkatachalam S, Tyner S, Pickering C, Boley S, Recio L, French J, et al.
Toxicol Pathol . 2001 Nov; 29 Suppl:147-54. PMID: 11695551
The p53 tumor suppressor gene has been shown to be critical in preventing cancer in humans and mice. We have generated and extensively characterized p53-deficient mice lacking one (p53+/-) or...
6.
Granstrand P, Nylander-French L, Lacks G, Holmstrom M, French J
Acta Otolaryngol . 2001 Oct; 121(6):743-9. PMID: 11678174
Symptoms of nasal, pharyngeal and ocular discomfort have been reported among workers in the wood surface-coating industry. Symptoms were reported more often by workers using ultraviolet radiation-curable acrylate coatings (UV...
7.
Martin K, Trempus C, Saulnier M, Kari F, Barrett J, French J
Carcinogenesis . 2001 Sep; 22(9):1373-8. PMID: 11532857
Epidemiologic studies support the protective role of dietary antioxidants in preventing cancer. However, emerging evidence from clinical trials and laboratory data suggest that in some cases individual antioxidant supplements may...
8.
Sills R, French J, Cunningham M
Toxicol Lett . 2001 Apr; 120(1-3):187-98. PMID: 11323177
Traditionally, the use of rodent models in assessing the carcinogenic potential of chemicals has been expensive and lengthy, and the relevance of the carcinogenic effect to humans is often not...
9.
Martin K, Kari F, Barrett J, French J
In Vitr Mol Toxicol . 2001 Apr; 13(4):237-48. PMID: 11319275
Recent epidemiological evidence suggests that antioxidants may enhance carcinogenesis by promoting cellular proliferation and/or impeding programmed cell death. We examined the effect of N-acetyl-l-cysteine (NAC) on mitogenesis and apoptosis in...
10.
Hulla J, French J, Dunnick J
Toxicol Sci . 2001 Mar; 60(2):264-70. PMID: 11248138
C57BL/6 p53 (+/-) N5 mice heterozygous for a null p53 allele were given phenolphthalein to learn more about mechanisms of carcinogenesis and to evaluate the p53-deficient mouse as a tool...