J de Gunzburg
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Explore the profile of J de Gunzburg including associated specialties, affiliations and a list of published articles.
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52
Citations
718
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Recent Articles
1.
Chilton C, Crowther G, Miossec C, de Gunzburg J, Andremont A, Wilcox M
J Antimicrob Chemother
. 2020 Feb;
75(6):1458-1465.
PMID: 32097465
Background: Clostridioides difficile infection (CDI) remains a high burden worldwide. DAV131A, a novel adsorbent, reduces residual gut antimicrobial levels, reducing CDI risk in animal models. Objectives: We used a validated...
2.
de Gunzburg J, Part D, Guiso N, Veron M
Biochemistry
. 2015 Oct;
23(17):3805-12.
PMID: 26485773
The CAMP-dependent protein kinase from Dictyostelium discoideum was extracted from cells at the stage of culmination. Less than 50% of the enzyme remains as a CAMP-dependent holoenzyme in the extracts,...
3.
Parrini M, Matsuda M, de Gunzburg J
Biochem Soc Trans
. 2005 Jul;
33(Pt 4):646-8.
PMID: 16042564
Pak1 (p21-activated kinase 1) is a key regulator of the actin cytoskeleton, adhesion and cell motility. Such biological roles require a tight spatial and kinetic control of its localization and...
4.
Rihet S, Vielh P, Camonis J, Goud B, Chevillard S, de Gunzburg J
J Cancer Res Clin Oncol
. 2002 Jan;
127(12):733-8.
PMID: 11768613
Purpose: The constitutive activation of Ras proteins by point mutation is the most frequently observed oncogene activation in human malignancies. The goal of this study was to investigate whether the...
5.
Mizenina O, Musatkina E, Yanushevich Y, Rodina A, Krasilnikov M, de Gunzburg J, et al.
J Biol Chem
. 2001 Jun;
276(36):34006-12.
PMID: 11427522
We have isolated a novel isoform of phospholipase A(2). This enzyme was designated srPLA(2) because it was discovered while analyzing the proteins interacting with different forms of the v-Src oncoproteins...
6.
Garcia J, de Gunzburg J, Eychene A, Gisselbrecht S, Porteu F
Mol Cell Biol
. 2001 Apr;
21(8):2659-70.
PMID: 11283246
Thrombopoietin (TPO) regulates growth and differentiation of megakaryocytes. We previously showed that extracellular signal-regulated kinases (ERKs) are required for TPO-mediated full megakaryocytic maturation in both normal progenitors and a megakaryoblastic...
7.
Callebaut I, de Gunzburg J, Goud B, Mornon J
Trends Biochem Sci
. 2001 Feb;
26(2):79-83.
PMID: 11166556
RUN domains are present in several proteins that are linked particularly to the functions of GTPases in the Rap and Rab families. They could hence play an important role in...
8.
Cho H, Kozasa T, Takekoshi K, de Gunzburg J, Kehrl J
Mol Pharmacol
. 2000 Aug;
58(3):569-76.
PMID: 10953050
Regulator of G protein signaling (RGS) proteins are a family of approximately 20 proteins that negatively regulate signaling through heterotrimeric G protein-coupled receptors. The RGS proteins act as GTPase-activating proteins...
9.
de Gunzburg J
Cell Biol Toxicol
. 2000 May;
15(6):345-58.
PMID: 10811529
Ras proteins are molecular switches that constitute a pivotal element in the control of cellular responses to many incoming signals, and in particular mitogenic stimulations. They act through multiple effector...
10.
El Ghouzzi V, Legeai-Mallet L, Aresta S, Benoist C, Munnich A, de Gunzburg J, et al.
Hum Mol Genet
. 2000 Apr;
9(5):813-9.
PMID: 10749989
H-TWIST belongs to the family of basic helix-loop-helix (bHLH) transcription factors known to exert their activity through dimer formation. We have demonstrated recently that mutations in H-TWIST account for Saethre-Chotzen...