J David Farrar
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Explore the profile of J David Farrar including associated specialties, affiliations and a list of published articles.
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39
Citations
1009
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Recent Articles
1.
von Itzstein M, Liu J, Mu-Mosley H, Fattah F, Park J, Sorelle J, et al.
JTO Clin Res Rep
. 2024 Dec;
6(1):100751.
PMID: 39619775
Introduction: Racial and ethnic disparities in the presentation and outcomes of lung cancer are widely known. To evaluate potential factors contributing to these observations, we measured systemic immune parameters in...
2.
von Itzstein M, Liu J, Mu-Mosley H, Fattah F, Park J, Sorelle J, et al.
bioRxiv
. 2024 Jun;
PMID: 38915535
Introduction: Racial and ethnic disparities in the presentation and outcomes of lung cancer are widely known. To evaluate potential factors contributing to these observations, we measured systemic immune parameters in...
3.
Vadhan J, Thoppil J, Vasquez O, Suarez A, Bartels B, McDonald S, et al.
J Emerg Med
. 2024 Jun;
67(2):e128-e137.
PMID: 38849253
Background: Sepsis is a life-threatening condition but predicting its development and progression remains a challenge. Objective: This study aimed to assess the impact of infection site on sepsis development among...
4.
Sharma D, Kohlbach K, Maples R, Farrar J
bioRxiv
. 2024 Apr;
PMID: 38559276
One Sentence Summary: The β2-adrenergic receptor regulates circadian gene oscillation and downstream daily timing of cytolytic T cell responses to virus infection.
5.
Thoppil J, Mehta P, Bartels B, Sharma D, Farrar J
Front Immunol
. 2023 Nov;
14:1271098.
PMID: 38022663
Sepsis is a major health problem in the United States (US), constituting a leading contributor to mortality among critically ill patients. Despite advances in treatment the underlying pathophysiology of sepsis...
6.
Chin Fatt C, Ayvaci E, Jha M, Emslie G, Gibson S, Minhajuddin A, et al.
J Affect Disord
. 2022 Dec;
325:55-61.
PMID: 36586601
Background: The suicide rate in youth and young adults continues to climb - we do not understand why this increase is occurring, nor do we have adequate tools to predict...
7.
Chin Fatt C, Farrar J, Jha M, Minhajuddin A, Mayes T, Foster J, et al.
Brain Behav Immun Health
. 2022 Sep;
25:100499.
PMID: 36120101
Background: To address the need to identify potential markers of suicide behavior for adolescents (ages 12-18 years), mass cytometry was used to explore the cellular mechanisms that may underpin immune...
8.
Estrada L, Agac Cobanoglu D, Wise A, Maples R, Cobanoglu M, Farrar J
PLoS One
. 2022 Aug;
17(8):e0272017.
PMID: 35944008
Norepinephrine is a key sympathetic neurotransmitter, which acts to suppress CD8 + T cell cytokine secretion and lytic activity by signaling through the β2-adrenergic receptor (ADRB2). Although ADRB2 signaling is...
9.
Gonugunta A, von Itzstein M, Mu-Mosley H, Fattah F, Farrar J, Mobely A, et al.
J Immunother Cancer
. 2021 Dec;
9(12).
PMID: 34880115
Immune-related adverse events (irAE) may affect almost any organ system and occur at any point during treatment with immune checkpoint inhibitors (ICI). We present a patient with advanced lung cancer...
10.