J David Farrar
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Explore the profile of J David Farrar including associated specialties, affiliations and a list of published articles.
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39
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1009
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Recent Articles
11.
Sharma D, Farrar J
Semin Immunopathol
. 2020 Nov;
42(6):709-717.
PMID: 33219396
The sympathetic nervous system integrates the functions of multiple organ systems by regulating their autonomic physiological activities. The immune system is regulated both locally and systemically by the neurotransmitters epinephrine...
12.
Rowe R, Pyle D, Farrar J, Gill M
Eur J Immunol
. 2020 May;
50(10):1550-1559.
PMID: 32383224
Rhinovirus (RV) infections are linked to the development and exacerbation of allergic diseases including allergic asthma. IgE, another contributor to atopic disease pathogenesis, has been shown to regulate DC antiviral...
13.
Lavery L, Davis K, La Fontaine J, Farrar J, Bhavan K, Oz O, et al.
Am J Surg
. 2020 Mar;
220(4):1076-1082.
PMID: 32139102
Aim: To compare the efficacy of Negative Pressure Wound Therapy (NPWT) with and without irrigation with 0.1% polyhexanide-betaine. Methods: We randomized 150 subjects in a 16-week RCT to compare healing...
14.
Chen F, Rowe R, Gill M, Farrar J
Allergy
. 2019 Sep;
75(3):695-698.
PMID: 31541610
No abstract available.
15.
Agac D, Estrada L, Maples R, Hooper L, Farrar J
Brain Behav Immun
. 2018 Sep;
74:176-185.
PMID: 30195028
The mammalian nervous system communicates important information about the environment to the immune system, but the underlying mechanisms are largely unknown. Secondary lymphoid organs are highly innervated by sympathetic neurons...
16.
Agac D, Gill M, Farrar J
Front Immunol
. 2018 Apr;
9:736.
PMID: 29696025
Upper respiratory viral infections are a major etiologic instigator of allergic asthma, and they drive severe exacerbations of allergic inflammation in the lower airways of asthma sufferers. Rhinovirus (RV), in...
17.
Estrada L, Agac D, Farrar J
Eur J Immunol
. 2016 May;
46(8):1948-58.
PMID: 27222010
Postganglionic sympathetic neurons innervate secondary lymphoid organs and secrete norepinephrine (NE) as the primary neurotransmitter. NE binds and signals through five distinct members of the adrenergic receptor family. In this...
18.
Gonzales-van Horn S, Estrada L, van Oers N, Farrar J
Eur J Immunol
. 2016 Mar;
46(6):1504-10.
PMID: 26990433
Type I interferon (IFN-α/β) plays a critical role in suppressing viral replication by driving the transcription of hundreds of interferon-sensitive genes (ISGs). While many ISGs are transcriptionally activated by the...
19.
Bajwa G, DeBerardinis R, Shao B, Hall B, Farrar J, Gill M
J Immunol
. 2016 Jan;
196(5):2004-9.
PMID: 26826244
Plasmacytoid dendritic cells (pDCs) are vital to antiviral defense, directing immune responses via secretion of huge concentrations of IFN-α. These cells are critical in protecting the lung against clinically relevant...
20.
Leigh N, Kokolus K, ONeill R, Du W, Eng J, Qiu J, et al.
J Immunol
. 2015 Oct;
195(10):5045-54.
PMID: 26459348
Graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic cell transplantation, a potentially curative therapy for hematologic diseases. It has long been thought that murine bone marrow-derived T cells...