J D Winkler
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Explore the profile of J D Winkler including associated specialties, affiliations and a list of published articles.
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66
Citations
1169
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Recent Articles
1.
Whelan K, Chandramouleeswaran P, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, et al.
Oncogene
. 2017 Apr;
36(34):4843-4858.
PMID: 28414310
High CD44 expression is associated with enhanced malignant potential in esophageal squamous cell carcinoma (ESCC), among the deadliest of all human carcinomas. Although alterations in autophagy and CD44 expression are...
2.
Evans L, Collins G, Shaffer R, Michelet V, Winkler J
Anal Chem
. 2011 Jun;
71(23):5322-7.
PMID: 21662730
The photoreversible metal-ion complexation behavior of nitroquinolinospiropyranindoline (NQSP) was studied in combination with the selective identification of six different transition-metal ions, Zn(2+), Co(2+), Hg(2+), Cu(2+), Cd(2+), and Ni(2+), in single-...
3.
Scott B, Zaratin P, Gilmartin A, Hansbury M, Colombo A, Belpasso C, et al.
Biochem Biophys Res Commun
. 2005 Feb;
328(2):409-14.
PMID: 15694363
Angiopoietin-1 (Ang-1) is one of a family of ligands for the Tie-2 receptor which has been demonstrated to be involved in angiogenesis. Little is known about the regulation of Ang-1...
4.
5.
Hansbury M, Nicosia R, Zhu W, Holmes S, Winkler J
Angiogenesis
. 2002 Feb;
4(1):29-36.
PMID: 11824375
The Tie2 receptor and its known ligands, the angiopoietins, play a critical role in endothelial cell differentiation during the process of angiogenesis. Recent experimental observations indicate that the agonistic ligand,...
6.
7.
Lee D, Long S, Murray J, Adams J, Nuttall M, Nadeau D, et al.
J Med Chem
. 2001 Jun;
44(12):2015-26.
PMID: 11384246
5-Dialkylaminosulfonylisatins have been identified as potent, nonpeptide inhibitors of caspases 3 and 7. The most active compound within this series (34) inhibited caspases 3 and 7 in the 2-6 nM...
8.
Nebulized sildenafil is a selective pulmonary vasodilator in lambs with acute pulmonary hypertension
Ichinose F, Hromi J, Raveh Y, Jones R, Krim L, Clark M, et al.
Crit Care Med
. 2001 May;
29(5):1000-5.
PMID: 11378612
Objective: To determine whether inhalation of aerosolized sildenafil with and without inhaled nitric oxide (NO) causes selective pulmonary vasodilation in a sheep model of pulmonary hypertension. Design: A controlled laboratory...
9.
Lee D, Long S, Adams J, Chan G, Vaidya K, Francis T, et al.
J Biol Chem
. 2000 May;
275(21):16007-14.
PMID: 10821855
Caspases have been strongly implicated to play an essential role in apoptosis. A critical question regarding the role(s) of these proteases is whether selective inhibition of an effector caspase(s) will...
10.
Zhou B, Chaturvedi P, Spring K, SCOTT S, Johanson R, Mishra R, et al.
J Biol Chem
. 2000 Apr;
275(14):10342-8.
PMID: 10744722
Recent evidence indicates that arrest of mammalian cells at the G(2)/M checkpoint involves inactivation and translocation of Cdc25C, which is mediated by phosphorylation of Cdc25C on serine 216. Data obtained...