J D Weinstein
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Explore the profile of J D Weinstein including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Luo M, Weinstein J, Walker C
Plant Mol Biol
. 2000 Mar;
41(6):721-31.
PMID: 10737137
Mg-chelatase catalyzes the insertion of Mg into protoporphyrin and lies at the branchpoint of heme and (bacterio)chlorophyll synthesis. In prokaryotes, three genes--BchI, D and H--encode subunits for Mg-chelatase. In higher...
2.
Datta C, Weinstein J, BLAND J, Brager P, Stewart M
W V Med J
. 1998 Nov;
94(5):276-8.
PMID: 9803886
This article presents a rare case of metastatic glioblastoma multiforme (GM) to the cervical lymph node. In spite of very aggressive tumor behavior, extracranial metastasis from intra-cerebral GM is rare....
3.
Walker C, Weinstein J
Biochem J
. 1994 Apr;
299 ( Pt 1):277-84.
PMID: 8166650
Mg(2+)-chelatase catalyses the first step unique to chlorophyll synthesis, namely the insertion of Mg2+ into protoporphyrin IX. When pea (Pisum sativum L., cv. Spring) chloroplasts are lysed in a buffer...
4.
Castelfranco P, Walker C, Weinstein J
Ciba Found Symp
. 1994 Jan;
180:194-204; discussion 205-9.
PMID: 7842853
The series of reactions leading from protoporphyrin IX to protochlorophyllide have been studied over the last 15 years in the authors' laboratories at Davis and Clemson. Here, two crucial steps...
5.
Weinstein J, Howell R, Leverette R, Grooms S, Brignola P, Mayer S, et al.
Plant Physiol
. 1993 Feb;
101(2):657-665.
PMID: 12231722
In plants, algae, and many bacteria, the heme and chlorophyll precursor, [delta]-aminolevulinic acid (ALA), is synthesized from glutamate in a reaction involving a glutamyl-tRNA intermediate and requiring ATP and NADPH...
6.
Walker C, Weinstein J
Proc Natl Acad Sci U S A
. 1991 Jul;
88(13):5789-93.
PMID: 11607197
The first committed step in chlorophyll synthesis is the Mg-chelatase-catalyzed insertion of magnesium into protoporphyrin IX. Since iron insertion into protoporphyrin leads to heme formation, Mg-chelastase lies at the branch...
7.
Walker C, Weinstein J
Plant Physiol
. 1991 Apr;
95(4):1189-96.
PMID: 16668110
Mg-chelatase catalyzes the first step unique to the chlorophyll branch of tetrapyrrole biosynthesis, namely the insertion of Mg into protoporphyrin IX (Proto). Mg-chelatase was assayed in intact chloroplasts from semi-green...
8.
Thomas J, Weinstein J
Plant Physiol
. 1990 Nov;
94(3):1414-23.
PMID: 16667847
Hemes destined for cytosolic hemoproteins must originate in one of the cellular compartments which have the capacity for heme synthesis, namely the chloroplast or the mitochondria. Since developing chloroplasts from...
9.
Mayer S, Beale S, Weinstein J
J Biol Chem
. 1987 Sep;
262(26):12541-9.
PMID: 2442164
Glutamate was converted to the chlorophyll and heme precursor delta-aminolevulinic acid in soluble extracts of Euglena gracilis. delta-Aminolevulinic acid-forming activity depended on the presence of native enzyme, glutamate, ATP, Mg2+,...
10.
Weinstein J, Mayer S, Beale S
Plant Physiol
. 1987 Jun;
84(2):244-50.
PMID: 16665424
Extracts from plant chloroplasts and algae catalyze the conversion of glutamate to delta-aminolevulinic acid (ALA) in the first committed step of the tetrapyrrole biosynthetic pathway leading to chlorophylls, hemes, and...