J D Hasday
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Explore the profile of J D Hasday including associated specialties, affiliations and a list of published articles.
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52
Citations
963
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Recent Articles
1.
Moore W, Hasday J, Meltzer S, Wisnewski P, White B, Bleecker E
J Allergy Clin Immunol
. 2001 Dec;
108(6):908-14.
PMID: 11742266
Background: The relationship between severity of asthma and bronchial inflammation is poorly understood. Objective: We examined acute and subacute inflammatory responses to allergen in subjects with mild and moderate persistent...
2.
De Boer M, Hu J, Kalvakolanu D, Hasday J, Cross A
J Interferon Cytokine Res
. 2001 Aug;
21(7):485-94.
PMID: 11506742
Interleukin-1 (IL-1) plays an important role in host defenses against microbial pathogens. Excessive production of this cytokine, however, may be responsible in part for the lethality observed during sepsis. Our...
3.
Manimtim W, Hasday J, Hester L, Fairchild K, Lovchik J, Viscardi R
Infect Immun
. 2001 May;
69(6):3906-15.
PMID: 11349058
We previously observed that Ureaplasma urealyticum respiratory tract colonization in infants with a birth weight of < or =1,250 g was associated with increases in the tracheal aspirate proinflammatory cytokines...
4.
Hasday J, Singh I
Cell Stress Chaperones
. 2001 Feb;
5(5):471-80.
PMID: 11189454
The heat shock response is an ancient and highly conserved process that is essential for surviving environmental stresses, including extremes of temperature. Fever is a more recently evolved response, during...
5.
Hasday J, Fairchild K, Shanholtz C
Microbes Infect
. 2001 Feb;
2(15):1891-904.
PMID: 11165933
Sepsis is a highly lethal clinical syndrome characterized by a systemic inflammatory response to infection. Fever, a non-specific acute-phase response, has been associated with improved survival and shortened disease duration...
6.
Fairchild K, Viscardi R, Hester L, Singh I, Hasday J
J Interferon Cytokine Res
. 2001 Jan;
20(12):1049-55.
PMID: 11152570
We have shown previously that febrile range temperatures modify cytokine production by adult macrophages. In this study, we compared the effects of moderate hyperthermia and hypothermia on the kinetics of...
7.
Hasday J, Bannerman D, Sakarya S, Cross A, Singh I, Howard D, et al.
J Appl Physiol (1985)
. 2001 Jan;
90(1):90-8.
PMID: 11133897
Fever is an important regulator of inflammation that modifies expression and bioactivity of cytokines, including tumor necrosis factor (TNF)-alpha. Pulmonary vascular endothelium is an important target of TNF-alpha during the...
8.
Hasday J, Garrison A
Clin Infect Dis
. 2000 Dec;
31 Suppl 5:S234-41.
PMID: 11113029
Sepsis is a clinical syndrome characterized by a systemic inflammatory response to infection. Mortality rates in sepsis have remained high, despite recent advances in our understanding of the immunological mechanisms...
9.
Hasday J, Meltzer S, Moore W, Wisniewski P, Hebel J, Lanni C, et al.
Am J Respir Crit Care Med
. 2000 Apr;
161(4 Pt 1):1229-36.
PMID: 10764316
The objective of this study was to determine the effects of allergen exposure on leukotriene generation and inflammation within the airways of allergic asthmatics and evaluate the effects of the...
10.
Singh I, Viscardi R, Kalvakolanu I, Calderwood S, Hasday J
J Biol Chem
. 2000 Mar;
275(13):9841-8.
PMID: 10734139
We previously reported that expression of tumor necrosis factor-alpha (TNFalpha) was attenuated in macrophages exposed to febrile range temperatures. In this study, we analyzed the influence of temperature on TNFalpha...