J D BRODIE
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Explore the profile of J D BRODIE including associated specialties, affiliations and a list of published articles.
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84
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1091
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Recent Articles
1.
Schiffer W, Gerasimov M, Hofmann L, Marsteller D, Ashby C, BRODIE J, et al.
Neuropsychopharmacology
. 2001 Oct;
25(5):704-12.
PMID: 11682254
To explore the role of endogenous GABA in NMDA antagonist induced dopamine (DA) release, we used in vivo microdialysis to study the effects of pretreatment with gamma-vinyl GABA (GVG) on...
2.
Horan B, Gardner E, Dewey S, BRODIE J, Ashby Jr C
Eur J Pharmacol
. 2001 Aug;
426(1-2):R1-2.
PMID: 11525784
We examined the effect of the sigma(1) receptor agonist, 1-(3,4-dimethoxyphenethyl)-4-(phenylpropyl)piperazine (SA4503), on the acquisition of the conditioned place preference response to subcutaneously administered (-)-nicotine in rats. (-)-Nicotine, but not SA4503...
3.
Paul M, Dewey S, Gardner E, BRODIE J, Ashby Jr C
Synapse
. 2001 Jun;
41(3):219-20.
PMID: 11391783
We examined the effect of gamma-vinyl GABA (GVG) on the expression of the conditioned place preference response to intraperitoneally (i.p.) administered heroin in rats. Heroin, but not vehicle, produced a...
4.
Gerasimov M, Schiffer W, Gardner E, Marsteller D, Lennon I, Taylor S, et al.
Eur J Pharmacol
. 2001 Mar;
414(2-3):205-9.
PMID: 11239920
Environments previously associated with drug use can become one of the most common factors triggering relapse to drug-seeking behavior. To better understand the neurochemical mechanisms potentially mediating these cues, we...
5.
Gerasimov M, Schiffer W, BRODIE J, Lennon I, Taylor S, Dewey S
Eur J Pharmacol
. 2000 May;
395(2):129-35.
PMID: 10794818
Dopaminergic activity in the mesocorticolimbic system is associated with reinforcing properties of psychostimulant drugs. We previously demonstrated that increased gamma-aminobutyric acid (GABA)-ergic activity produced by gamma-vinyl GABA [D,L-4-amino-hex-5-enoic acid (Vigabatrin(R))],...
6.
Schiffer W, Gerasimov M, Bermel R, BRODIE J, Dewey S
Life Sci
. 2000 Mar;
66(13):PL169-73.
PMID: 10737423
Elevation of endogenous GABA by the racemic mixture of gamma vinyl-GABA (GVG, Vigabatrin) decreases extracellular nucleus accumbens (NAc) dopamine (DA) levels and diminishes the response to many drugs of abuse...
7.
Hutchinson M, SCHIFFER W, Joseffer S, Liu A, Schlosser R, Dikshit S, et al.
Magn Reson Imaging
. 1999 Dec;
17(10):1427-36.
PMID: 10609991
In general, image analysis of cognitive experiments using functional magnetic resonance imaging techniques has emphasized those regions of the brain where increases in signal intensity, with regard to the reference...
8.
Gerasimov M, Ashby Jr C, Gardner E, Mills M, BRODIE J, Dewey S
Synapse
. 1999 Aug;
34(1):11-9.
PMID: 10459167
We examined the acute effect of the irreversible GABA-transaminase inhibitor, gamma-vinyl GABA (GVG, Sabril((R)), Vigabatrin((R))) on increases in nucleus accumbens (NAc) dopamine (DA) following acute administration of methamphetamine, heroin, or...
9.
Dewey S, BRODIE J, Gerasimov M, Horan B, Gardner E, Ashby Jr C
Synapse
. 1999 Feb;
31(1):76-86.
PMID: 10025686
Like many psychostimulant drugs, nicotine elevates extracellular and synaptic dopamine (DA) concentrations in the nucleus accumbens (NAc). This elevation has been linked to its reinforcing properties. Dopaminergic transmission within the...
10.
Ashby Jr C, Rohatgi R, Ngosuwan J, Borda T, Gerasimov M, Morgan A, et al.
Synapse
. 1999 Feb;
31(2):151-3.
PMID: 10024012
Previously, we demonstrated that gamma vinyl-GABA (GVG, Vigabatrin) dose-dependently inhibits cocaine-induced increases in dopamine (DA) concentrations in both the rodent and primate brain. Furthermore, it abolishes cocaine self-administration and conditioned...