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C R Ashby Jr

Explore the profile of C R Ashby Jr including associated specialties, affiliations and a list of published articles. Areas
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Articles 75
Citations 741
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Recent Articles
1.
Fu X, Dong X, Zeng L, Ashby Jr C, Chen Z, Cheng C
Drugs Today (Barc) . 2021 Sep; 57(9):559-569. PMID: 34586104
The identification of oncogenic drivers and the subsequent development of targeted therapies have been established as biomarker-based care for metastatic non-small cell lung cancer (NSCLC) patients. Rearranged during transfection (RET)...
2.
Li L, Zou C, Dong S, Wu Z, Ashby Jr C, Chen Z, et al.
Drugs Today (Barc) . 2021 Jun; 57(6):377-385. PMID: 34151904
Small cell lung cancer (SCLC) is a rapidly progressive, aggressive metastatic and lethal subtype of lung cancer. Unfortunately, there has been little progress regarding the development of novel treatments for...
3.
Puglisi G, Smith S, Jankovich R, Ashby Jr C, Jodlowski T
J Clin Pharm Ther . 2016 Nov; 42(1):115-118. PMID: 27813106
What Is Known And Objective: Paritaprevir/ritonavir/ombitasvir+dasabuvir (PrOD) is a direct-acting antiviral (DAA) approved for the treatment of chronic hepatitis C virus. We report on a probable interaction between PrOD with...
4.
Gerasimov M, Ferrieri R, Schiffer W, Logan J, Gatley S, Gifford A, et al.
Life Sci . 2002 Sep; 70(23):2811-28. PMID: 12269385
Inhalant abuse is a rapidly growing health problem particularly among adolescents. Yet we know little about the neural mechanisms underlying the abuse liability of inhalants, particularly when compared to other...
5.
Horan B, Gardner E, Dewey S, BRODIE J, Ashby Jr C
Eur J Pharmacol . 2001 Aug; 426(1-2):R1-2. PMID: 11525784
We examined the effect of the sigma(1) receptor agonist, 1-(3,4-dimethoxyphenethyl)-4-(phenylpropyl)piperazine (SA4503), on the acquisition of the conditioned place preference response to subcutaneously administered (-)-nicotine in rats. (-)-Nicotine, but not SA4503...
6.
Paul M, Dewey S, Gardner E, BRODIE J, Ashby Jr C
Synapse . 2001 Jun; 41(3):219-20. PMID: 11391783
We examined the effect of gamma-vinyl GABA (GVG) on the expression of the conditioned place preference response to intraperitoneally (i.p.) administered heroin in rats. Heroin, but not vehicle, produced a...
7.
Slusher B, Thomas A, Paul M, Schad C, Ashby Jr C
Synapse . 2001 May; 41(1):22-8. PMID: 11354010
In this study we examined the effect of 2-(phosphonomethyl)pentanedioic acid (2-PMPA) and GPI 5693, selective inhibitors of the enzyme N-Acetylated-alpha-Linked-Acidic Dipeptidase (NAALADase; glutamate carboxypeptidase II; EC no. 3.4.17.21), which cleaves...
8.
Tajiri K, Emori K, Murata M, Tanaka K, Suzuki M, Uehara T, et al.
Synapse . 2001 Apr; 40(4):275-81. PMID: 11309843
In this study, we determined the activity of midbrain dopamine (DA) neurons in male albino rats following the intracerebroventricular (i.c.v.) administration of antisense oligodeoxynucleotide (aODN) against the mRNA for the...
9.
Hirose S, Ashby Jr C, Mills M
J ECT . 2001 Apr; 17(1):22-6. PMID: 11281510
Aggressive behavior in schizophrenic patients can often be problematic not only for the patients themselves, but for their families and others. This study examined the effect of electroconvulsive therapy (ECT)...
10.
Minabe Y, Hashimoto K, Watanabe K, Ashby Jr C
Synapse . 2001 Mar; 40(2):102-12. PMID: 11252021
We examined the effect of the acute and repeated administration of M100907 (formerly MDL 100907), a selective 5-HT(2A) receptor antagonist, on spontaneously active dopamine (DA) neurons in the substantia nigra...