J D Bjorge
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Explore the profile of J D Bjorge including associated specialties, affiliations and a list of published articles.
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19
Citations
471
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Recent Articles
1.
Zhu S, Bjorge J, Cheng H, Fujita D
Oncogene
. 2007 Oct;
27(14):2027-34.
PMID: 17934522
Src activation has been associated with colon cancers but the mechanism underlying Src activation is largely unknown. Csk-homologous kinase (CHK) can inhibit the kinase activity of certain Src kinase family...
2.
Bjorge J, Jakymiw A, Fujita D
Oncogene
. 2000 Dec;
19(49):5620-35.
PMID: 11114743
Since the discovery of the v-src and c-src genes and their products, much progress has been made in the elucidation of the structure, regulation, localization, and function of the Src...
3.
Bjorge J, Pang A, Fujita D
J Biol Chem
. 2000 Sep;
275(52):41439-46.
PMID: 11007774
c-Src tyrosine kinase activity is elevated in several types of human cancer, and this has been attributed to elevated c-Src expression levels, increased c-Src specific activity, and activating mutations in...
4.
Waltenberger J, Uecker A, Kroll J, Frank H, Mayr U, Bjorge J, et al.
Circ Res
. 1999 Jul;
85(1):12-22.
PMID: 10400906
PP1 has previously been described as an inhibitor of the Src-family kinases p56(Lck) and FynT. We have therefore decided to use PP1 to determine the functional role of Src in...
5.
Sicilia R, Hibbs M, Bello P, Bjorge J, Fujita D, Stanley I, et al.
J Biol Chem
. 1998 Jun;
273(27):16756-63.
PMID: 9642231
Hck and Src are members of the Src family of protein- tyrosine kinases that carry out distinct and overlapping functions in vivo (Lowell, C. A., Niwa, M., Soriano, P., and...
6.
Johnson T, Perich J, Bjorge J, Fujita D, Cheng H
J Pept Res
. 1997 Dec;
50(5):365-71.
PMID: 9401921
The relative efficiencies of the catalytic domain of the src-family kinase pp60c-src in phosphorylating four peptide substrates including (i) src-optimal peptide (AEEEIYGEFEAKKKK), (ii) "-YEEI-peptide" (KKTHQEEEEPQYEEIPIYL), (iii) cdc2(6-20) (KVEKIGEGTYGVVYK), (iv) src-autophosphorylation...
7.
Bellagamba C, Hubaishy I, Bjorge J, Fitzpatrick S, Fujita D, Waisman D
J Biol Chem
. 1997 Feb;
272(6):3195-9.
PMID: 9013554
In the present article we have examined if the interaction of the Ca2+-binding protein, annexin II tetramer (AIIt) with the plasma membrane phospholipids or with the submembranous cytoskeleton, effects the...
8.
Cheng H, Bjorge J, Aebersold R, Fujita D, Wang J
Biochemistry
. 1996 Sep;
35(36):11874-87.
PMID: 8794770
The C-terminal src kinase (CSK) is a ubiquitously expressed, cytosolic enzyme capable of phosphorylating and inactivating several plasma membrane-bound src-family protein tyrosine kinases in vitro [Nada, S., Okada, M., MacAuley,...
9.
Bjorge J, OConnor T, Fujita D
Biochem Cell Biol
. 1996 Jan;
74(4):477-84.
PMID: 8960354
pp60c-src and the structurally related members of the Src family are non-receptor tyrosine kinases that reside within the cell associated with cell membranes and appear to transduce signals from transmembrane...
10.
Bjorge J, Bellagamba C, Cheng H, Tanaka A, Wang J, Fujita D
J Biol Chem
. 1995 Oct;
270(41):24222-8.
PMID: 7592628
Two activated transforming mutants of human pp60c-src were found to possess single point mutations within the regulatory carboxyl terminus (E527K in CY CST201) and the kinase domain (E381G in WO...