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J D Alvarez

Explore the profile of J D Alvarez including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 469
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Recent Articles
1.
Connors D, Allen J, Alvarez J, Boyle J, Cristofanilli M, Hiller C, et al.
Crit Rev Oncol Hematol . 2020 Oct; 156:103112. PMID: 33035734
The promise of precision medicine as a model to customize health care to the individual patient is heavily dependent upon new genetic tools to classify and characterize diseases and their...
2.
Abeysekara A, Albert A, Alfaro R, Alvarez C, Alvarez J, Arceo R, et al.
Nature . 2018 Nov; 564(7736):E38. PMID: 30482938
In this Letter, owing to a production error, the penultimate version of the PDF was published. The HTML version was always correct. The PDF has been corrected online.
3.
Abeysekara A, Albert A, Alfaro R, Alvarez C, Alvarez J, Arceo R, et al.
Nature . 2018 Oct; 562(7725):82-85. PMID: 30283106
SS 433 is a binary system containing a supergiant star that is overflowing its Roche lobe with matter accreting onto a compact object (either a black hole or neutron star)....
4.
Abeysekara A, Albert A, Alfaro R, Alvarez C, Alvarez J, Arceo R, et al.
Science . 2017 Nov; 358(6365):911-914. PMID: 29146808
The unexpectedly high flux of cosmic-ray positrons detected at Earth may originate from nearby astrophysical sources, dark matter, or unknown processes of cosmic-ray secondary production. We report the detection, using...
5.
Alvarez J, Hansen A, Ord T, Bebas P, Chappell P, Giebultowicz J, et al.
J Biol Rhythms . 2008 Feb; 23(1):26-36. PMID: 18258755
Although it is well established that the circadian clock regulates mammalian reproductive physiology, the molecular mechanisms by which this regulation occurs are not clear. The authors investigated the reproductive capacity...
6.
Alvarez J, Sehgal A
J Biol Rhythms . 2005 Apr; 20(2):111-21. PMID: 15834108
The molecular basis for the circadian clock in mammals consists of a number of genes and proteins that form transcription-translation feedback loops. These loops result in a 24-h rhythm in...
7.
Alvarez J, Chen D, Storer E, Sehgal A
Biol Reprod . 2003 Feb; 69(1):81-91. PMID: 12606319
The central circadian clock in mammals is housed in the brain and is based on cyclic transcription and translation of clock proteins. How the central clock regulates peripheral organ function...
8.
Alvarez J, Sehgal A
Nature . 2002 Oct; 419(6909):798-9. PMID: 12397342
No abstract available.
9.
Alvarez J, Sehgal A
Dev Cell . 2002 Aug; 3(2):150-2. PMID: 12194843
Circadian rhythms are generated by a transcription/translation feedback loop consisting of two limbs, one positive and one negative. The nuclear orphan receptor, REV-ERBalpha, is identified as a molecular link coupling...
10.
Alvarez J, Yasui D, Niida H, Joh T, Loh D, Kohwi-Shigematsu T
Genes Dev . 2000 Mar; 14(5):521-35. PMID: 10716941
SATB1 is expressed primarily in thymocytes and can act as a transcriptional repressor. SATB1 binds in vivo to the matrix attachment regions (MARs) of DNA, which are implicated in the...