J Cossman
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Explore the profile of J Cossman including associated specialties, affiliations and a list of published articles.
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Articles
127
Citations
2302
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Recent Articles
1.
Woosley R, Cossman J
Clin Pharmacol Ther
. 2006 Dec;
81(1):129-33.
PMID: 17186012
Advances in biomedical research over recent decades have substantially raised expectations that the pharmaceutical industry will generate increasing numbers of safe and effective therapies. However, there are warning signs of...
2.
Cossman J
J Histochem Cytochem
. 2001 May;
49(6):799-800.
PMID: 11373330
The origin of the Reed-Sternberg cell of Hodgkin's disease remained clouded in mystery for almost a century after its discovery in 1898. The major obstacle to its understanding is that,...
3.
Annunziata C, Safiran Y, Irving S, Kasid U, Cossman J
Blood
. 2000 Oct;
96(8):2841-8.
PMID: 11023520
The malignant Reed-Sternberg cell of Hodgkin disease is an aberrant B cell that persists in an immunolgically mediated inflammatory infiltrate. Despite its nonproductive immunoglobulin genes, the Reed-Sternberg cell avoids the...
4.
Cossman J, Annunziata C, Barash S, Staudt L, Dillon P, He W, et al.
Blood
. 1999 Jul;
94(2):411-6.
PMID: 10397707
The malignant Reed-Sternberg cell of Hodgkin's disease, first described a century ago, has resisted in-depth analysis due to its extreme rarity in lymphomatous tissue. To directly study its genome-wide gene...
5.
Kallakury B, Hartmann D, Cossman J, Gootenberg J, Bagg A
Am J Clin Pathol
. 1999 Jun;
111(6):759-66.
PMID: 10361511
Flow cytometric immunophenotypic analysis is critical in diagnosis and classification of acute leukemia and has been used after therapy to monitor for minimal residual disease. However, the presence of normal...
6.
7.
Ozdemirli M, Fanburg-Smith J, Hartmann D, Shad A, Lage J, Magrath I, et al.
Am J Surg Pathol
. 1998 Jul;
22(7):795-804.
PMID: 9669342
Precursor B-lymphoblastic lymphoma (B-LBL) may present as a solitary bone tumor. Fewer than 10 cases with a proven precursor B-cell phenotype have been reported in the English literature. In this...
8.
KAMESAKI H, Nishizawa K, Michaud G, Cossman J, Kiyono T
J Immunol
. 1998 Apr;
160(2):770-7.
PMID: 9551912
TGF-beta1 inhibits the cell cycle progression of many types of cells by arresting them in the G1 phase. This cell cycle arrest has been attributed to the regulatory effects of...
9.
Messineo C, Jamerson M, Hunter E, Braziel R, Bagg A, Irving S, et al.
Blood
. 1998 Apr;
91(7):2443-51.
PMID: 9516144
Although Hodgkin's disease is highly responsive to treatments that cause apoptosis, it remains resistant to the physiological mechanisms intended to cause cell death. Presumably, the Reed-Sternberg cell defies endogenous apoptosis,...
10.
Cossman J, Messineo C, Bagg A
Lab Invest
. 1998 Apr;
78(3):229-35.
PMID: 9520936
In contrast to the non-Hodgkin's lymphomas, little is known regarding the origin, genetics, and function of the Reed-Sternberg cell of Hodgkin's disease. Unlike other cancers, the neoplastic cell of Hodgkin's...