J Conover
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Explore the profile of J Conover including associated specialties, affiliations and a list of published articles.
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25
Citations
541
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Recent Articles
1.
Klinman D, Conover J, Bloom E, Weiss W
J Gerontol A Biol Sci Med Sci
. 2008 Mar;
53(4):B281-6.
PMID: 18314558
The immunogenicity and protective efficacy of a DNA vaccine encoding the circumsporozoite protein of the Plasmodium yoelii malaria parasite was evaluated in young (2 months) versus aged (>26 months) BALB/c...
2.
Jones E, Conover J, Symes A
J Biol Chem
. 2000 Aug;
275(46):36013-20.
PMID: 10964933
The neuropoietic cytokine ciliary neurotrophic factor (CNTF) potently induces transcription of the vasoactive intestinal peptide (VIP) gene through a 180-base pair (bp) cytokine response element (CyRE) in the VIP promoter....
3.
Symes A, Pitts R, Conover J, Kos K, Coulombe J
Mol Endocrinol
. 2000 Mar;
14(3):429-39.
PMID: 10707960
Activin, a member of the transforming growth factor-beta superfamily, can regulate neuropeptide gene expression in the nervous system and in neuroblastoma cells. Among the neuropeptide genes whose expression can be...
4.
Klinman D, Conover J, Coban C
Infect Immun
. 1999 Oct;
67(11):5658-63.
PMID: 10531213
Synthetic oligodeoxynucleotides (ODN) expressing unmethylated CpG motifs stimulate an innate immune response characterized by the production of polyreactive immunoglobulin M antibodies and immunomodulatory cytokines. This immune response has been shown...
5.
Ichino M, Mor G, Conover J, Weiss W, Takeno M, Ishii K, et al.
J Immunol
. 1999 Apr;
162(7):3814-8.
PMID: 10201898
A plasmid DNA vaccine encoding the circumsporozoite protein of malaria (pCSP) induces tolerance rather than immunity when administered to newborn mice. We find that this tolerance persists for >1 yr...
6.
Klinman D, Conover J, Leiden J, Rosenberg A, Sechler J
Hum Gene Ther
. 1999 Mar;
10(4):659-65.
PMID: 10094209
This work examines the effect of delivering a DNA plasmid encoding murine erythropoietin (pVRmEpo) to BALB/c mice by gene gun. Whereas intramuscular injection elicits a rise in hematocrit persisting >8...
7.
Klinman D, Barnhart K, Conover J
Vaccine
. 1999 Mar;
17(1):19-25.
PMID: 10078603
Bacterial DNA contains immunostimulatory motifs that trigger an innate immune response characterized by the production of predominantly Th1-type cytokines. These motifs consist of an unmethylated CpG dinucleotide flanked by two...
8.
9.
Gilkeson G, Conover J, Halpern M, Pisetsky D, Feagin A, Klinman D
J Immunol
. 1998 Oct;
161(8):3890-5.
PMID: 9780154
Microbial DNA has multiple immune effects including the capacity to induce polyclonal B cell activation and cytokine production in normal mice. We recently described the accelerated induction of anti-DNA Abs...
10.
Klinman D, Sechler J, Conover J, Gu M, Rosenberg A
J Immunol
. 1998 Mar;
160(5):2388-92.
PMID: 9498781
Gene gun-mediated DNA vaccination stimulates an immune response characterized by the activation of IgG-secreting B cells and IFN-gamma-secreting T cells. To monitor the contribution of cells at the site of...