J C Ruegg
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Explore the profile of J C Ruegg including associated specialties, affiliations and a list of published articles.
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189
Citations
2143
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Recent Articles
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Galler S, Kogler H, Ivemeyer M, Ruegg J
Pflugers Arch
. 1999 Oct;
438(4):525-30.
PMID: 10519147
Isometric force responses following flash photolysis of caged-ATP were measured from skinned preparations of the catch muscle anterior byssus retractor of Mytilus (ABRM). When fibres were transferred from Ca(2+)-free to...
3.
Geyer M, Strauss J, Ruegg J, Kogler H
Pflugers Arch
. 1999 Oct;
438(4):470-8.
PMID: 10519140
Myofilament Ca2+ desensitization contributes to the contractile dysfunction of ischemic/reperfused ("stunned") myocardium. We examined the presence of reduced Ca2+ sensitivity of isometric force in chemically skinned fibers obtained from stunned...
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Ruegg J
Naturwissenschaften
. 1999 Jan;
85(12):575-82.
PMID: 9871917
In both cardiac and skeletal muscle, the force-generating molecular motors (crossbridges) are turned on by increasing the intracellular free calcium level that regulates the troponin-tropomyosin system. However, calcium activation is...
6.
McAinsh A, Geyer M, Fandrey J, Ruegg J, Wiesner R
Mol Cell Biochem
. 1998 Oct;
187(1-2):141-6.
PMID: 9788751
Left ventricular hypertrophy (LVH) is often associated with an impaired maximal coronary blood flow and increases the vulnerability of the heart tissue to ischaemia. In this study, the correlation between...
7.
Kogler H, Plathow C, Trayer I, Ruegg J
Pflugers Arch
. 1998 Jun;
436(3):398-406.
PMID: 9644222
We extracted troponin-I (TnI) from skinned rat and rabbit soleus muscle fibres using a modification of the method described by Strauss et al. (FEBS Lett 310:229-234, 1992) for replacement of...
8.
Lubke E, Freiburg A, Skeie G, Kolmerer B, Labeit S, Aarli J, et al.
J Neuroimmunol
. 1998 Apr;
81(1-2):98-108.
PMID: 9521611
Myasthenia gravis (MG) patients develop autoantibodies primarily against the acetylcholine receptor in the motor endplate, but also against intracellular striated muscle proteins, notably titin, the giant elastic protein of the...
9.
Albrecht K, Schneider A, Liebetrau C, Ruegg J, Pfitzer G
Pflugers Arch
. 1997 Aug;
434(5):534-42.
PMID: 9242716
In smooth muscle, the state of prolonged contraction (latch state) is associated with very slow energy turnover and cycling of crossbridges that are dephosphorylated. A similar state may be reproduced...
10.
Linke W, Ivemeyer M, Labeit S, Hinssen H, Ruegg J, Gautel M
Biophys J
. 1997 Aug;
73(2):905-19.
PMID: 9251807
The high stiffness of relaxed cardiac myofibrils is explainable mainly by the expression of a short-length titin (connectin), the giant elastic protein of the vertebrate myofibrillar cytoskeleton. However, additional molecular...