J C McDermott
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Explore the profile of J C McDermott including associated specialties, affiliations and a list of published articles.
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88
Citations
780
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Recent Articles
1.
Tobin S, Hashemi S, Dadson K, Turdi S, Ebrahimian K, Zhao J, et al.
Sci Rep
. 2017 Jul;
7(1):4476.
PMID: 28667250
Myocyte Enhancer Factor 2 (MEF2) mediates cardiac remodelling in heart failure (HF) and is also a target of β-adrenergic signalling, a front-line treatment for HF. We identified global gene transcription...
2.
Hashemi S, Salma J, Wales S, McDermott J
Cell Death Discov
. 2016 Aug;
1:15019.
PMID: 27551452
β1-Adrenergic receptor (β1-AR) stimulation increases apoptosis in cardiomyocytes through activation of cAMP/protein kinase A (PKA) signaling. The myocyte enhancer factor 2 (MEF2) proteins function as important regulators of myocardial gene...
3.
Mughal W, Nguyen L, Pustylnik S, da Silva Rosa S, Piotrowski S, Chapman D, et al.
Cell Death Dis
. 2015 Oct;
6:e1944.
PMID: 26512955
Exposure to metabolic disease during fetal development alters cellular differentiation and perturbs metabolic homeostasis, but the underlying molecular regulators of this phenomenon in muscle cells are not completely understood. To...
4.
Hashemi S, Wales S, Miyake T, McDermott J
Cell Death Dis
. 2015 Oct;
6:e1916.
PMID: 26469965
No abstract available.
5.
Dionyssiou M, Ehyai S, Avrutin E, Connor M, McDermott J
Cell Death Dis
. 2014 Mar;
5:e1094.
PMID: 24577092
MYOGENIN is a member of the muscle regulatory factor family that orchestrates an obligatory step in myogenesis, the terminal differentiation of skeletal muscle cells. A paradoxical feature of alveolar rhabdomyosarcoma...
6.
Alli N, Yang E, Miyake T, Aziz A, Collins-Hooper H, Patel K, et al.
Cell Death Dis
. 2013 Jun;
4:e692.
PMID: 23807221
Activator protein-1 (AP-1) is a ubiquitous transcription factor that paradoxically also has some tissue-specific functions. In skeletal muscle cells, we document that the AP-1 subunit, Fra-2, is expressed in the...
7.
Dionyssiou M, Nowacki N, Hashemi S, Zhao J, Kerr A, Tsushima R, et al.
J Mol Cell Cardiol
. 2012 Nov;
54:35-44.
PMID: 23137781
Characterizing the signaling network that controls MEF2 transcription factors is crucial for understanding skeletal and cardiac muscle gene expression. Glycogen synthase kinase 3β (GSK3β) regulates MEF2 activity indirectly through reciprocal...
8.
Perry R, Yang C, Soora N, Salma J, Marback M, Naghibi L, et al.
Mol Cell Biol
. 2009 Apr;
29(12):3355-66.
PMID: 19364819
The myocyte enhancer factor 2 (MEF2) transcription factors play important roles in neuronal, cardiac, and skeletal muscle tissues. MEF2 serves as a nuclear sensor, integrating signals from several signaling cascades...
9.
Selwyn R, Avila-Rodriguez M, Converse A, Hampel J, Jaskowiak C, McDermott J, et al.
Phys Med Biol
. 2007 Dec;
52(24):7397-408.
PMID: 18065846
(90)Y-labeled resin microspheres (SIR-Spheres) are currently used to treat patients with primary and metastatic solid liver tumors. This treatment is typically palliative since patients have exhausted all other standard treatment...
10.
Cox D, Zhong F, Du M, Duchoslav E, Sakuma T, McDermott J
J Biomol Tech
. 2005 Jul;
16(2):83-90.
PMID: 16030315
The activity of many transcriptional regulators is significantly altered by posttranslational modifications of specific sites. For example, the activity of the muscle-restricted transcription factor family myocyte enhancer factor 2 (MEF2)...