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J C Marini

Explore the profile of J C Marini including associated specialties, affiliations and a list of published articles. Areas
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Articles 75
Citations 1172
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Recent Articles
1.
Blouin S, Fratzl-Zelman N, Roschger A, Cabral W, Klaushofer K, Marini J, et al.
J Mech Behav Biomed Mater . 2018 Oct; 90:125-132. PMID: 30366302
Higher skeletal fragility has been established for the Brtl/+ mouse model of osteogenesis imperfecta at the whole bone level, but previous investigations of mechanical properties at the bone material level...
2.
Lowes S, Hucker R, Jemal M, Marini J, Rezende V, Shoup R, et al.
AAPS J . 2014 Oct; 17(1):17-23. PMID: 25338740
The A2 harmonization team, a part of the Global Bioanalysis Consortium (GBC), focused on defining possible tiers of chromatographic-based bioanalytical method performance. The need for developing bioanalytical methods suitable for...
3.
Sinder B, White L, Salemi J, Ominsky M, Caird M, Marini J, et al.
Osteoporos Int . 2014 May; 25(8):2097-107. PMID: 24803333
Unlabelled: Treatments to reduce fracture rates in adults with osteogenesis imperfecta are limited. Sclerostin antibody, developed for treating osteoporosis, has not been explored in adults with OI. This study demonstrates...
4.
Meganck J, Begun D, McElderry J, Swick A, Kozloff K, Goldstein S, et al.
Bone . 2013 Jun; 56(1):204-12. PMID: 23774443
Osteogenesis imperfecta (OI) is a heritable bone dysplasia characterized by increased skeletal fragility. Patients are often treated with bisphosphonates to attempt to reduce fracture risk. However, bisphosphonates reside in the...
5.
Valli M, Barnes A, Gallanti A, Cabral W, Viglio S, Weis M, et al.
Clin Genet . 2011 Sep; 82(5):453-9. PMID: 21955071
Deficiency of any component of the ER-resident collagen prolyl 3-hydroxylation complex causes recessive osteogenesis imperfecta (OI). The complex modifies the α1(I)Pro986 residue and contains cartilage-associated protein (CRTAP), prolyl 3-hydroxylase 1...
6.
Blair-Levy J, WATTS C, Fiorentino N, Fiorientino N, Dimitriadis E, Marini J, et al.
Arthritis Rheum . 2008 Apr; 58(4):1096-106. PMID: 18383364
Objective: This study was undertaken to test the hypothesis that abnormalities of the subchondral bone can result in osteoarthritis (OA). Methods: We used a knockin model of human osteogenesis imperfecta,...
7.
Marini J, Fox D, Murphy M
J Anim Sci . 2007 Dec; 86(3):660-79. PMID: 18073282
In ruminant animals, endogenous N (EN) secretions contribute to meeting the N requirement of the ruminal microflora. The EN also constitutes a sizable portion of the duodenal N flow, which...
8.
Visvanathan S, Wagner C, Marini J, Baker D, Gathany T, Han J, et al.
Ann Rheum Dis . 2007 Jul; 67(4):511-7. PMID: 17644552
Objective: To evaluate the relationship between biomarker levels and disease activity and the spinal inflammation detected by magnetic resonance imaging (MRI) in patients with ankylosing spondylitis (AS). Methods: Patients with...
9.
Cabral W, Milgrom S, Letocha A, Moriarty E, Marini J
J Med Genet . 2006 Aug; 43(8):685-90. PMID: 16882741
Background: The biochemical test for osteogenesis imperfecta (OI) detects structural abnormalities in the helical region of type I collagen as delayed electrophoretic migration of alpha chains on SDS-urea-PAGE. Sensitivity of...
10.
Marini J, Lee B, Garlick P
Lab Anim . 2006 Jun; 40(3):275-81. PMID: 16803644
We have developed and validated catheterization protocols in mice that allow for simultaneous infusion and sampling. A sampling catheter was inserted in the lateral vein of the tail, while the...