J C Marine
Overview
Explore the profile of J C Marine including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
1034
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0
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Recent Articles
1.
Pendeville H, Carpino N, Marine J, Takahashi Y, Muller M, Martial J, et al.
Mol Cell Biol
. 2001 Sep;
21(19):6549-58.
PMID: 11533243
Overexpression and inhibitor studies have suggested that the c-Myc target gene for ornithine decarboxylase (ODC), the enzyme which converts ornithine to putrescine, plays an important role in diverse biological processes,...
2.
Moriggl R, Marine J, Topham D, Teglund S, Sexl V, Mckay C, et al.
Cold Spring Harb Symp Quant Biol
. 2001 Mar;
64:389-95.
PMID: 11232312
No abstract available.
3.
Wen R, Wang D, Mckay C, Bunting K, Marine J, Vanin E, et al.
Mol Cell Biol
. 2001 Jan;
21(2):678-89.
PMID: 11134353
Jak3-deficient mice display vastly reduced numbers of lymphoid cells. Thymocytes and peripheral T cells from Jak3-deficient mice have a high apoptotic index, suggesting that Jak3 provides survival signals. Here we...
4.
Wang D, Feng J, Wen R, Marine J, Sangster M, Parganas E, et al.
Immunity
. 2000 Aug;
13(1):25-35.
PMID: 10933392
Many receptors activate phospholipase Cgamma1 or -gamma2. To assess the role of PLCgamma2, we derived enzyme-deficient mice. The mice are viable but have decreased mature B cells, a block in...
5.
Wang D, Moriggl R, Stravopodis D, Carpino N, Marine J, Teglund S, et al.
EMBO J
. 2000 Feb;
19(3):392-9.
PMID: 10654938
Cytokines induce the tyrosine phosphorylation and associated activation of signal transducers and activators of transcription (Stat). The mechanisms by which this response is terminated are largely unknown. Among a variety...
6.
Kieslinger M, Woldman I, Moriggl R, Hofmann J, Marine J, Ihle J, et al.
Genes Dev
. 2000 Feb;
14(2):232-44.
PMID: 10652277
Stat5 is activated by multiple receptors of hematopoietic cytokines. To study its role during hematopoiesis, we have generated primary chicken myeloblasts expressing different dominant-negative (dn) alleles of Stat5. This caused...
7.
Marine J, Mckay C, Wang D, Topham D, Parganas E, Nakajima H, et al.
Cell
. 1999 Sep;
98(5):617-27.
PMID: 10490101
SOCS3 (CIS3/JAB2) is an SH2-containing protein that binds to the activation loop of Janus kinases, inhibiting kinase activity, and thereby suppressing cytokine signaling. During embryonic development, SOCS3 is highly expressed...
8.
Marine J, Topham D, Mckay C, Wang D, Parganas E, Stravopodis D, et al.
Cell
. 1999 Sep;
98(5):609-16.
PMID: 10490100
SOCS1 is an SH2-containing protein that is primarily expressed in thymocytes in a cytokine- and T cell receptor-independent manner. SOCS1 deletion causes perinatal lethality with death by 2-3 weeks. During...
9.
Poncelet D, Bellefroid E, Bastiaens P, Demoitie M, Marine J, Pendeville H, et al.
DNA Cell Biol
. 1998 Dec;
17(11):931-43.
PMID: 9839802
We previously identified the ZNF85 (HPF4) KRAB zinc finger gene, a member of the human ZNF91 family. Here, we show that the ZNF85 gene is highly expressed in normal adult...
10.
Parganas E, Wang D, Stravopodis D, Topham D, Marine J, Teglund S, et al.
Cell
. 1998 May;
93(3):385-95.
PMID: 9590173
A variety of cytokines activate receptor-associated members of the Janus family of protein tyrosine kinases (Jaks). To assess the role of Jak2, we have derived Jak2-deficient mice. The mutation causes...