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J C Mansfield

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Articles 30
Citations 437
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Recent Articles
11.
Lamb C, Mohiuddin M, Gicquel J, Neely D, Bergin F, Hanson J, et al.
Br J Surg . 2009 Apr; 96(6):663-74. PMID: 19384912
Background: Identifying Crohn's disease recurrence in symptomatic patients after ileocaecal resection is difficult. The aim of this study was to evaluate faecal concentrations of granulocyte degradation products in this setting....
12.
Mansfield J, Parkes M, Hawthorne A, Forbes A, Probert C, Perowne R, et al.
Aliment Pharmacol Ther . 2007 Jul; 26(3):421-30. PMID: 17635377
Background: Therapy targeted at tumour necrosis factor-alpha has an established role in Crohn's disease. Lenalidomide, an analogue of thalidomide, is an oral immunomodulatory agent with powerful antitumour necrosis factor-alpha properties....
13.
Todhunter C, Sutherland-Craggs A, Bartram S, Donaldson P, Daly A, Francis R, et al.
Gut . 2005 Jul; 54(11):1579-84. PMID: 16009674
Background: Osteoporosis is an important cause of morbidity in patients with Crohn's disease. The pathogenesis of reduced bone mineral density (BMD) is multifactorial. A range of genetic factors have been...
14.
Johnson G, Cosnes J, Mansfield J
Aliment Pharmacol Ther . 2005 Apr; 21(8):921-31. PMID: 15813828
This article aims to offer an updated review of the effects of smoking on inflammatory bowel disease, and provide a review of the methods of achieving smoking cessation. A systematic...
15.
Wayman J, Mansfield J, Matthewson K, Richardson D, Griffin S
Hepatogastroenterology . 2003 Jul; 50(52):915-8. PMID: 12845949
Background/aims: In patients with obstructive jaundice, when the endoscopic approach fails to achieve biliary drainage, percutaneous cannulation and combined endoscopic/percutaneous endoprosthesis insertion can be performed simultaneously or in stages. This...
16.
Gunn M, Cavin A, Mansfield J
Postgrad Med J . 2003 Apr; 79(929):154-8. PMID: 12697915
The diagnosis of irritable bowel syndrome (IBS) is made on clinical grounds with appropriate limited investigations to exclude organic disease. IBS is common and may have a significant impact on...
17.
Mansfield J
Gut . 2003 Apr; 52(5):771. PMID: 12692073
No abstract available.
18.
Mansfield J, Giaffer M, Cann P, McKenna D, Thornton P, HOLDSWORTH C
Aliment Pharmacol Ther . 2002 Feb; 16(1):69-77. PMID: 11856080
Background: Sulfasalazine is accepted therapy for active ulcerative colitis, but side-effects and intolerance are common. Balsalazide is an azo-bonded pro-drug which also releases 5-aminosalicylic acid into the colon, but uses...
19.
Green J, Mansfield J, Gibson J, Kerr G, Thornton P
Aliment Pharmacol Ther . 2002 Feb; 16(1):61-8. PMID: 11856079
Background: Sulfasalazine is well established in the treatment of active ulcerative colitis. Intolerance to sulfasalazine, however, is a common problem. Balsalazide has been designed to deliver 5-aminosalicylic acid to the...
20.
Aithal G, Craggs A, Day C, Welfare M, Daly A, Mansfield J, et al.
Dig Dis Sci . 2001 Aug; 46(7):1520-5. PMID: 11478505
Interleukin-10 (IL-10) has a key role in regulating mucosal inflammation. The role of functional polymorphisms at positions -627 and -1117 in the IL-10 gene as candidate susceptibility loci in inflammatory...