C D HOLDSWORTH
Overview
Explore the profile of C D HOLDSWORTH including associated specialties, affiliations and a list of published articles.
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113
Citations
1778
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Recent Articles
1.
Mansfield J, Giaffer M, Cann P, McKenna D, Thornton P, HOLDSWORTH C
Aliment Pharmacol Ther
. 2002 Feb;
16(1):69-77.
PMID: 11856080
Background: Sulfasalazine is accepted therapy for active ulcerative colitis, but side-effects and intolerance are common. Balsalazide is an azo-bonded pro-drug which also releases 5-aminosalicylic acid into the colon, but uses...
2.
Verma S, HOLDSWORTH C, Giaffer M
Scand J Gastroenterol
. 2001 May;
36(4):383-8.
PMID: 11336163
Background: Nutritional therapy plays an important role in the management of Crohn disease, particularly during the acute phase. Nutritional supplementation may also prevent relapses during the quiescent phase of Crohn...
3.
Green J, Gibson J, Kerr G, Swarbrick E, Lobo A, HOLDSWORTH C, et al.
Aliment Pharmacol Ther
. 1999 Jan;
12(12):1207-16.
PMID: 9882028
Background: Despite widespread use of aminosalicylates as maintenance treatment for ulcerative colitis (UC), patients still report troublesome symptoms, often nocturnally. Aim: To compare the efficacy and safety of balsalazide (Colazide)...
4.
5.
Green J, Lobo A, HOLDSWORTH C, Leicester R, Gibson J, Kerr G, et al.
Gastroenterology
. 1998 Jan;
114(1):15-22.
PMID: 9428213
Background & Aims: Aminosalicylates are widely used in the treatment of ulcerative colitis (UC). Balsalazide is a novel mesalamine prodrug, activated by colonic bacteria. The aim of this study was...
6.
Mansfield J, Giaffer M, Tindale W, HOLDSWORTH C
Gut
. 1995 Nov;
37(5):679-83.
PMID: 8549945
The ideal imaging method in inflammatory bowel disease would reliably detect inflammation, identify the correct intestinal location, and assess the severity of the disease. The aim of this study was...
7.
Mansfield J, Giaffer M, HOLDSWORTH C
Gut
. 1995 Jan;
36(1):60-6.
PMID: 7890238
Elemental diets are effective in inducing remission in active Crohn's disease, but how they exert this therapeutic effect is unclear. In a previous study a whole protein containing diet proved...
8.
Mansfield J, HOLDEN H, Tarlow J, Di Giovine F, McDowell T, Wilson A, et al.
Gastroenterology
. 1994 Mar;
106(3):637-42.
PMID: 8119534
Background/aims: Ulcerative colitis and Crohn's disease have well-recognized familial tendencies, but the genetic basis of this clinical observation remains unknown. The cytokine interleukin-1 receptor antagonist is a potent anti-inflammatory protein...
9.
Giaffer M, Tindale W, HOLDSWORTH C
Scand J Gastroenterol Suppl
. 1994 Jan;
203:55-60.
PMID: 7973451
A computer-based technique for the quantification of abnormal bowel uptake in Crohn's disease has been developed and compared with pre-existing clinical, laboratory and scintigraphic methods of assessment. The standard technique...
10.
Giaffer M, Tindale W, Senior S, Barber D, HOLDSWORTH C
Gut
. 1993 Jan;
34(1):68-74.
PMID: 8432455
The reliability and clinical applications of computerised image analysis measurement of bowel uptake of Tc-99m HMPAO labelled leucocytes has been examined as a measure of disease activity in Crohn's disease....