J C Garcia-Borron
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Explore the profile of J C Garcia-Borron including associated specialties, affiliations and a list of published articles.
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66
Citations
700
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Recent Articles
1.
Cerdido S, Abrisqueta M, Sanchez-Beltran J, Lambertos A, Castejon-Grinan M, Munoz C, et al.
Cancer Lett
. 2023 Nov;
581:216484.
PMID: 38008393
Mahogunin Ring Finger 1 is an E3-ubiquitin ligase encoded by the color gene MGRN1. Our previous in vitro and in vivo studies demonstrated that Mgrn1 deletion in mouse melanoma cells...
2.
Stefanaki I, Stratigos A, Kypreou K, Evangelou E, Gandini S, Maisonneuve P, et al.
J Eur Acad Dermatol Venereol
. 2020 Aug;
35(2):e135-e138.
PMID: 32780924
No abstract available.
3.
Tagliabue E, Fargnoli M, Gandini S, Maisonneuve P, Liu F, Kayser M, et al.
Br J Cancer
. 2015 Jun;
113(2):354-63.
PMID: 26103569
Background: The melanocortin-1-receptor (MC1R) gene regulates human pigmentation and is highly polymorphic in populations of European origins. The aims of this study were to evaluate the association between MC1R variants...
4.
Sanchez-Laorden B, Sanchez-Mas J, Turpin M, Garcia-Borron J, Jimenez-Cervantes C
Cell Mol Biol (Noisy-le-grand)
. 2006 Aug;
52(2):39-46.
PMID: 16914085
The alpha melanocyte-stimulating hormone receptor (MC1R) is a heptahelical G protein-coupled receptor (GPCR) found in the plasma membrane of melanocytes. By mediating the melanogenic response to melanocortins, MC1R is a...
5.
Sanchez-Mas J, Sanchez-Laorden B, Guillo L, Jimenez-Cervantes C, Garcia-Borron J
Peptides
. 2005 Jul;
26(10):1848-57.
PMID: 15993512
The pigmentary actions of the melanocortins are mediated by the melanocortin-1 receptor (MC1R), a seven transmembrane domains receptor positively coupled to Gs and the cAMP cascade. In order to define...
6.
Eves P, Haycock J, Layton C, Wagner M, Kemp H, Szabo M, et al.
Br J Cancer
. 2003 Nov;
89(10):2004-15.
PMID: 14612916
Alpha-melanocyte stimulating hormone (alpha-MSH) is known to have pleiotrophic functions including pigmentary, anti-inflammatory, antipyretic and immunoregulatory roles in the mammalian body. It is also reported to influence melanoma invasion with...
7.
Solano F, Hearing V, Garcia-Borron J
Neurotox Res
. 2003 Jul;
1(3):153-69.
PMID: 12835099
o-Quinones are easily formed by oxidation of physiologically relevant catechols. These reactions mainly occur in two specialized cells, catecholaminergic neurons and melanocytes. Both types of cells are related ontogenetically, as...
8.
Jimenez-Cervantes C, Germer S, Gonzalez P, Sanchez J, Sanchez C, Garcia-Borron J
FEBS Lett
. 2001 Nov;
508(1):44-8.
PMID: 11707265
Activation by melanocortins of the melanocortin 1 receptor (MC1R), expressed in epidermal melanocytes, stimulates melanogenesis. Human MC1R gene loss-of-function mutations are associated with fair skin, poor tanning and increased skin...
9.
Jimenez-Cervantes C, Martinez-Esparza M, Perez C, Daum N, Solano F, Garcia-Borron J
J Cell Sci
. 2001 Aug;
114(Pt 12):2335-44.
PMID: 11493672
H(2)O(2) and other reactive oxygen species are key regulators of many intracellular pathways. Within mammalian skin, H(2)O(2) is formed as a byproduct of melanin synthesis, and following u.v. irradiation. We...
10.
Martinez-Esparza M, Ferrer C, Castells M, Garcia-Borron J, Zuasti A
Int J Biochem Cell Biol
. 2001 Jul;
33(10):971-83.
PMID: 11470231
Transforming growth factor-beta1 (TGFbeta1) downregulates tyrosinase in B16 melanoma cells by decreasing gene expression and the intracellular half-life of the enzyme, but does not block tyrosinase stimulation by alpha-melanocyte stimulating...