J Bruggink
Overview
Explore the profile of J Bruggink including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
38
Followers
0
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Recent Articles
1.
Bailey H, Tutsch K, Arzoomanian R, Tombes M, Alberti D, Bruggink J, et al.
Cancer Res
. 1991 Feb;
51(4):1105-8.
PMID: 1705165
A phase I trial of fazarabine (ara-AC, 1-beta-D-arabinofuranosyl-5-azacytosine, NSC 281272) administered as a 24-h continuous infusion was performed in 24 adults with solid tumor malignancies. The majority of patients had...
2.
Remick S, Grem J, FISCHER P, Tutsch K, Alberti D, Nieting L, et al.
Cancer Res
. 1990 May;
50(9):2667-72.
PMID: 2328492
Forty-seven patients with advanced malignancies were treated with a concurrent 72-h continuous infusion of 5-fluorouracil (FUra) and dipyridamole. The FUra dose was escalated over the dose range of 185 to...
3.
WILLSON J, FISCHER P, Remick S, Tutsch K, Grem J, Nieting L, et al.
Cancer Res
. 1989 Apr;
49(7):1866-70.
PMID: 2924325
We have carried out a clinical trial in 23 patients to determine whether dipyridamole modulates the clinical effect of methotrexate. This trial was based upon in vitro studies which indicate...
4.
FISCHER P, WILLSON J, RisueNo C, Tutsch K, Bruggink J, Ranhosky A, et al.
Cancer Res
. 1988 Oct;
48(19):5591-6.
PMID: 3416312
Since this Phase I trial was based on a strategy of biochemical modulation, namely, the inhibition of nucleoside uptake by dipyridamole, a biochemical assessment of the actions of acivicin and...
5.
WILLSON J, FISCHER P, Tutsch K, Alberti D, Simon K, HAMILTON R, et al.
Cancer Res
. 1988 Oct;
48(19):5585-90.
PMID: 3416311
A Phase I clinical trial of simultaneous 72-h infusions of dipyridamole and acivicin was carried out in patients with advanced malignancies. The objective of this trial was to determine the...
6.
FISCHER P, Fang T, Lin T, Hampton A, Bruggink J
Biochem Pharmacol
. 1988 Apr;
37(7):1293-8.
PMID: 3355601
The effects of a variety of 5-, 5'-, and 3'-substituted deoxyuridine derivatives on the cytoplasmic thymidine kinase (EC 2.7.1.21) purified from a human colon carcinoma cell line, HCT 116, were...
7.
Strubbe J, Prins A, Bruggink J, Steffens A
J Auton Nerv Syst
. 1987 Aug;
20(2):113-9.
PMID: 3312380
Rats were provided with permanent cardiac catheters allowing free movement and blood sampling without anaesthesia. During food intake the increments of plasma insulin and blood glucose were smaller and more...