J Brandon White
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Explore the profile of J Brandon White including associated specialties, affiliations and a list of published articles.
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8
Citations
356
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Recent Articles
1.
Farshbaf M, Lindberg M, Truong A, Bevens Z, Chambers E, Pournara A, et al.
PLoS One
. 2015 Jul;
10(7):e0134013.
PMID: 26225565
Early studies demonstrated the involvement of ubiquitination of the Notch intracellular domain for rapid turnover of the transcriptional complex at Notch target genes. It was shown that this ubiquitination was...
2.
Yadegarynia S, Pham A, Ng A, Nguyen D, Lialiutska T, Bortolazzo A, et al.
Nat Prod Commun
. 2014 Jul;
9(5):597-606.
PMID: 25026697
Flavonoids have been shown to be cytotoxic to cancer cells. However, the mechanism of cytotoxicity has not been clearly defined. It has previously been reported that HER2/ERBB2, the estrogen receptor,...
3.
Yadegarynia S, Pham A, Ng A, Nguyen D, Lialiutska T, Bortolazzo A, et al.
Nat Prod Commun
. 2012 Nov;
7(10):1295-304.
PMID: 23156993
Flavonoids have been shown to be cytotoxic to cancer cells. However, the mechanism of cytotoxicity has not been clearly defined. It has previously been reported that HER2/ERBB2, the estrogen receptor,...
4.
Pham A, Bortolazzo A, White J
Biochem Biophys Res Commun
. 2012 Sep;
427(2):415-20.
PMID: 23000408
Quercetin is a member of the flavonoid family and has been previously shown to have a variety of anti-cancer activities. We and others have reported anti-proliferation, cell cycle arrest, and...
5.
White J, Beckford J, Yadegarynia S, Ngo N, Lialiutska T, dAlarcao M
Food Chem
. 2011 Dec;
131(4):1453-1459.
PMID: 22140296
A common feature of both apoptosis and inflammation is the activation of caspases. Caspases are aspartate-directed cysteine proteases that have numerous cellular targets. It has been discovered that several flavonoids...
6.
Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover
Fryer C, White J, Jones K
Mol Cell
. 2004 Nov;
16(4):509-20.
PMID: 15546612
Notch signaling releases the Notch receptor intracellular domain (ICD), which complexes with CBF1 and Mastermind (MAM) to activate responsive genes. We previously reported that MAM interacts with CBP/p300 and promotes...
7.
White J, Thompson W, Pittler S
Mol Vis
. 2004 Oct;
10:738-49.
PMID: 15480303
Purpose: Previous studies identified rod photoreceptor cyclic GMP phosphodiesterase (PDE6) transcripts in the human Y79 retinoblastoma cell line. To assess the potential to utilize this cell line for structure/function studies...
8.
Pittler S, Zhang Y, Chen S, Mears A, Zack D, Ren Z, et al.
J Biol Chem
. 2004 Mar;
279(19):19800-7.
PMID: 15001570
To understand the factors controlling expression of the cGMP phosphodiesterase type 6 (PDE6) genes, we have characterized the promoter of the human PDE6A gene that encodes the catalytic alpha-subunit. In...