J Bockaert
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Explore the profile of J Bockaert including associated specialties, affiliations and a list of published articles.
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344
Citations
6658
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Recent Articles
1.
Hinsinger G, Galeotti N, Nabholz N, Urbach S, Rigau V, Demattei C, et al.
Mult Scler
. 2015 Feb;
21(10):1251-61.
PMID: 25698171
Background: Despite sensitivity of MRI to diagnose multiple sclerosis (MS), prognostic biomarkers are still needed for optimized treatment. Objective: The objective of this paper is to identify cerebrospinal fluid (CSF)...
2.
Jean A, Laurent L, Bockaert J, Charnay Y, Dusticier N, Nieoullon A, et al.
Transl Psychiatry
. 2012 Dec;
2:e203.
PMID: 23233022
In mental diseases, the brain does not systematically adjust motor activity to feeding. Probably, the most outlined example is the association between hyperactivity and anorexia in Anorexia nervosa. The neural...
3.
Nicoletti F, Bockaert J, Collingridge G, Conn P, Ferraguti F, Schoepp D, et al.
Neuropharmacology
. 2010 Nov;
60(7-8):1017-41.
PMID: 21036182
Metabotropic glutamate (mGlu) receptors were discovered in the mid 1980s and originally described as glutamate receptors coupled to polyphosphoinositide hydrolysis. Almost 6500 articles have been published since then, and subtype-selective...
4.
Sebben-Perez M, Ebersolt C, Blanc G, Bockaert J
Neurochem Int
. 2010 May;
6(1):103-8.
PMID: 20488027
Rat corpus striatum contained ?(2)-adrenergic receptor which were labelled with [(3)H]clonidine (95 +/- 6 fmol/mg protein). The affinity of these receptors (K(d) = 1.3 to 3.6 nM) was similar to...
5.
Chanrion B, Mannoury la Cour C, Bertaso F, Lerner-Natoli M, Freissmuth M, Millan M, et al.
Proc Natl Acad Sci U S A
. 2007 Apr;
104(19):8119-24.
PMID: 17452640
The spatiotemporal regulation of neurotransmitter transporters involves proteins that interact with their intracellular domains. Using a proteomic approach, we identified several proteins that interact with the C terminus of the...
6.
Libeer C, Bockaert J, Van den Brande P, Zachee P, van de Vyvere M, Geyskens W
Acta Clin Belg
. 2005 Nov;
60(4):173-9.
PMID: 16279397
The Lemierre syndrome or 'necrobacillosis' is a post angina sepsis caused by an acute oropharyngeal infection with a secondary thrombophlebitis of the internal jugular vein. There are often septic emboli...
7.
Marchetti E, Chaillan F, Dumuis A, Bockaert J, Soumireu-Mourat B, Roman F
Neuropharmacology
. 2004 Nov;
47(7):1021-35.
PMID: 15555636
Firstly, olfactory association learning was used to determine the modulating effect of 5-HT4 receptor involvement in learning and long-term memory. Secondly, the effects of systemic injections of a 5-HT4 partial...
8.
Bockaert J, Roussignol G, Becamel C, Gavarini S, Joubert L, Dumuis A, et al.
Biochem Soc Trans
. 2004 Oct;
32(Pt 5):851-5.
PMID: 15494032
The simplistic idea that seven transmembrane receptors are single monomeric proteins that interact with heterotrimeric G-proteins after agonist binding is definitively out of date. Indeed, GPCRs (G-protein-coupled receptors) are part...
9.
Bockaert J, Claeysen S, Compan V, Dumuis A
Curr Drug Targets CNS Neurol Disord
. 2004 Feb;
3(1):39-51.
PMID: 14965243
Serotonin 4 receptors (5-HT(4)Rs) were discovered 15 years ago. They are coded by a very complex gene (700Kb, 38 exons) which generates eight carboxy-terminal variants (a, b, c, d, e,...
10.
Jamen F, Alonso G, Shibuya I, Widmer H, Vacher C, Calas A, et al.
J Neuroendocrinol
. 2003 Aug;
15(9):871-81.
PMID: 12899682
The role of pituitary adenylate cyclase-activating polypeptide (PACAP) type I receptor (PAC1 receptor) in regulating hypothalamic supraoptic neurones was investigated using PAC1 receptor-deficient male mice (PAC1-/-). The effects of PACAP...