J B Tuttle
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Explore the profile of J B Tuttle including associated specialties, affiliations and a list of published articles.
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64
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1074
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Recent Articles
21.
Steers W, Broder S, Persson K, Bruns D, Ferguson 2nd J, Bruns M, et al.
J Urol
. 1998 Aug;
160(3 Pt 1):908-12.
PMID: 9720586
Parathyroid hormone-related protein (PTHrP) immunoreactivity has been detected in the bladder and increases in response to dilatation secondary to obstruction. The hypothesis that PTHrP could be increased solely by stretch...
22.
Sherer T, Neff P, Hankins G, Tuttle J
Exp Cell Res
. 1998 Jun;
241(1):186-93.
PMID: 9633527
The spontaneously hypertensive rat (SHR) was developed as a genetic model of essential hypertension. In vivo and in vitro evidence demonstrates that vascular smooth muscle cells (VSMCs) from the SHR...
23.
Spitsbergen J, Clemow D, McCarty R, Steers W, Tuttle J
Brain Res
. 1998 Jun;
790(1-2):151-9.
PMID: 9593870
The development of hypertension in spontaneously hypertensive rats (SHR) and hyperactive voiding in rats with urethral obstruction are characterized by abnormal smooth muscle growth, increased tissue levels of nerve growth...
24.
Sherer T, Spitsbergen J, Steers W, Tuttle J
Cell Tissue Res
. 1997 Jul;
289(1):155-61.
PMID: 9182610
The production of nerve growth factor (NGF) in peripheral organs may play a role in the pathophysiology of hypertension and in obstructive disorders of the bladder outlet. We have been...
25.
Sheehan J, Swerdlow R, Miller S, Davis R, Parks J, Parker W, et al.
J Neurosci
. 1997 Jun;
17(12):4612-22.
PMID: 9169522
Alzheimer's disease (AD) is associated with defects in mitochondrial function. Mitochondrial-based disturbances in calcium homeostasis, reactive oxygen species (ROS) generation, and amyloid metabolism have been implicated in the pathophysiology of...
26.
Sheehan J, PALMER P, Helm G, Tuttle J
J Neurosci Res
. 1997 May;
48(3):226-37.
PMID: 9160245
PD is a common, late-onset neurodegenerative disorder that results in part from the gradual loss of dopaminergic neurons in the substantia nigra pars compacta. The neurotoxin MPTP can induce PD-like...
27.
Persson K, Steers W, Tuttle J
J Urol
. 1997 May;
157(5):2000-6.
PMID: 9112580
Purpose: Interest in the regulation of nerve growth factor (NGF) production in the urinary tract derives from its probable involvement in obstructive, inflammatory and developmental disorders. This study examines receptor-mediated...
28.
Sheehan J, Swerdlow R, Parker W, Miller S, Davis R, Tuttle J
J Neurochem
. 1997 Mar;
68(3):1221-33.
PMID: 9048769
Parkinson's disease may be linked to defects in mitochondrial function. Mitochondrially transformed cells (cybrids) were created from Parkinson's disease patients or disease-free controls. Parkinson's disease cybrids had 26% less complex...
29.
Creedon D, Tuttle J
J Neurosci Res
. 1997 Feb;
47(3):277-86.
PMID: 9039650
Vascular smooth muscle (VSM) cells comprise one of the primary targets of the sympathetic nervous system and have been shown to secrete nerve growth factor (NGF). There is increasing evidence...
30.
Clemow D, McCarty R, Steers W, Tuttle J
Neurourol Urodyn
. 1997 Jan;
16(4):293-303.
PMID: 9220478
Elevated nerve growth factor secreted by bladder smooth muscle may be associated with noradrenergic hyperinnervation of the bladder and hyperactive voiding in spontaneously hypertensive rats (SHR) and rats with bladder...