J B Tuttle
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Explore the profile of J B Tuttle including associated specialties, affiliations and a list of published articles.
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64
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1074
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Recent Articles
11.
The effect of sildenafil on apomorphine-evoked increases in intracavernous pressure in the awake rat
Andersson K, Gemalmaz H, Waldeck K, Chapman T, Tuttle J, Steers W
J Urol
. 1999 Apr;
161(5):1707-12.
PMID: 10210444
Purpose: The aim of this study was to develop a quantitative, awake animal model to investigate the effect of sildenafil on centrally-evoked erectile activity. Methods: Intracavernous pressures were recorded in...
12.
Chai T, Gemalmaz H, Andersson K, Tuttle J, Steers W
J Urol
. 1999 Apr;
161(5):1689-93.
PMID: 10210441
Purpose: Bladder outlet obstruction (BOO) can increase urinary frequency. Even after surgical relief of obstruction, up to 30% of patient are still bothered by irritative voiding symptoms. We tested the...
13.
Clemow D, Spitsbergen J, McCarty R, Steers W, Tuttle J
J Urol
. 1999 Mar;
161(4):1372-7.
PMID: 10081910
Purpose: Hyperactive voiding and elevated smooth muscle NGF output are traits of the spontaneously hypertensive rat (SHR). Elevated target-derived NGF is associated with hypertension and hyperactive voiding in SHRs. In...
14.
Steers W, Clemow D, Persson K, Sherer T, Andersson K, Tuttle J
Exp Physiol
. 1999 Mar;
84(1):137-47.
PMID: 10081714
Recent epidemiological studies have shown that hypertensive men are more likely to undergo surgical intervention for irritative voiding symptoms from BPH than age-matched controls. Indeed, noradrenergic nerves which regulate vascular...
15.
Sherer T, Neff P, Tuttle J
Brain Res Mol Brain Res
. 1998 Nov;
62(2):167-74.
PMID: 9813306
Altered nerve growth factor (NGF) regulation has been linked to the pathophysiology of hypertension. Vascular smooth muscle cells from an inbred hypertensive, but normoactive rat strain (WKHT) secreted NGF at...
16.
Clemow D, Tuttle J
Cell Tissue Res
. 1998 Nov;
294(3):431-8.
PMID: 9799460
Elevated target-derived smooth muscle nerve growth factor (NGF) and resultant neurogenic plasticity are associated with both hypertension and hyperactive voiding in spontaneously hypertensive rats (SHRs: hypertensive, behaviorally hyperactive). In culture,...
17.
Clemow D, Spitsbergen J, McCarty R, Steers W, Tuttle J
Exp Cell Res
. 1998 Oct;
244(1):196-205.
PMID: 9770362
Elevated levels of nerve growth factor (NGF) protein and NGF mRNA have been reported in the vessels of spontaneously hypertensive rats (SHR: hypertensive, hyperactive) compared to Wistar-Kyoto (WKY) rats. Elevated...
18.
Persson K, Pandita R, Spitsbergen J, Steers W, Tuttle J, Andersson K
Am J Physiol
. 1998 Oct;
275(4):R1366-73.
PMID: 9756570
The influence of noradrenergic mechanisms involved in micturition in spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats was investigated using continuous cystometry in in vivo and in vitro studies on...
19.
Clemow D, Steers W, McCarty R, Tuttle J
Am J Physiol
. 1998 Oct;
275(4):R1279-86.
PMID: 9756561
Elevated bladder smooth muscle cell (BSMC) nerve growth factor (NGF) secretion and related neuroplasticity are associated with hyperactive voiding in spontaneously hypertensive rats (SHRs: hypertensive, behaviorally hyperactive), compared with control...
20.
Swerdlow R, Parks J, Cassarino D, Trimmer P, Miller S, Maguire D, et al.
Exp Neurol
. 1998 Sep;
153(1):135-42.
PMID: 9743575
Mitochondria are abnormal in persons with amyotrophic lateral sclerosis (ALS) for unknown reasons. We explored whether aberration of mitochondrial DNA (mtDNA) could play a role in this by transferring mitochondrial...