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J B Rafferty

Explore the profile of J B Rafferty including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 717
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Recent Articles
1.
Bailey S, Sedelnikova S, Mesa P, Ayora S, Alonso J, Rafferty J
Acta Crystallogr D Biol Crystallogr . 2003 Jun; 59(Pt 6):1090-2. PMID: 12777784
The essential helicase loader protein G39P encoded by Bacillus subtilis SPP1 phage has been overproduced in Escherichia coli and purified. The wild-type protein has been crystallized by the hanging-drop vapour-diffusion...
2.
Abdelghany H, Gasmi L, Cartwright J, Bailey S, Rafferty J, McLennan A
Biochim Biophys Acta . 2001 Dec; 1550(1):27-36. PMID: 11738085
Asymmetrically cleaving diadenosine 5',5"'-P(1),P(4)-tetraphosphate (Ap4A) hydrolase activity has been detected in extracts of adult Caenorhabditis elegans and the corresponding cDNA amplified and expressed in Escherichia coli. As expected, sequence analysis...
3.
Levy C, Baldock C, Wallace A, Sedelnikova S, Viner R, Clough J, et al.
J Mol Biol . 2001 Aug; 309(1):171-80. PMID: 11491286
Enoyl acyl carrier protein (ACP) reductase catalyses the last reductive step of fatty acid biosynthesis, reducing the enoyl group of a growing fatty acid chain attached to ACP to its...
4.
Turnbull A, Rafferty J, Sedelnikova S, Slabas A, Schierer T, Kroon J, et al.
Structure . 2001 May; 9(5):347-53. PMID: 11377195
Background: Glycerol-3-phosphate (1)-acyltransferase(G3PAT) catalyzes the incorporation of an acyl group from either acyl-acyl carrier proteins (acylACPs) or acyl-CoAs into the sn-1 position of glycerol 3-phosphate to yield 1-acylglycerol-3-phosphate. G3PATs can...
5.
Sedelnikova S, Smits S, Leonard P, Brinkman A, van der Oost J, Rafferty J, et al.
Acta Crystallogr D Biol Crystallogr . 2001 May; 57(Pt 6):886-8. PMID: 11375518
The LrpA transcriptional regulator from Pyrococcus furiosus, a member of the leucine-responsive regulatory protein (Lrp) family, has been crystallized by the hanging-drop method of vapour diffusion using ammonium sulfate as...
6.
McLeod R, Muench S, Rafferty J, Kyle D, Mui E, Kirisits M, et al.
Int J Parasitol . 2001 Mar; 31(2):109-13. PMID: 11239932
Fab I, enoyl acyl carrier protein reductase (ENR), is an enzyme used in fatty acid synthesis. It is a single chain polypeptide in plants, bacteria, and mycobacteria, but is part...
7.
Leonard P, Smits S, Sedelnikova S, Brinkman A, de Vos W, van der Oost J, et al.
EMBO J . 2001 Mar; 20(5):990-7. PMID: 11230123
The LrpA protein from the hyperthermophilic archaeon Pyrococcus furiosus belongs to the Lrp/AsnC family of transcriptional regulatory proteins, of which the Escherichia coli leucine-responsive regulatory protein is the archetype. Its...
8.
Turnbull A, Rafferty J, Sedelnikova S, Slabas A, Schierer T, Kroon J, et al.
Acta Crystallogr D Biol Crystallogr . 2001 Feb; 57(Pt 3):451-3. PMID: 11223529
Glycerol-3-phosphate 1-acyltransferase (E.C. 2.3.1.15; G3PAT) catalyses the incorporation of an acyl group from either acyl-acyl carrier proteins (acylACPs) or acylCoAs into the sn-1 position of glycerol 3-phosphate to yield 1-acylglycerol...
9.
Fisher M, Kroon J, Martindale W, Stuitje A, Slabas A, Rafferty J
Structure . 2000 May; 8(4):339-47. PMID: 10801480
Background: beta-Keto acyl carrier protein reductase (BKR) catalyzes the pyridine-nucleotide-dependent reduction of a 3-oxoacyl form of acyl carrier protein (ACP), the first reductive step in de novo fatty acid biosynthesis...
10.
Fisher M, Sedelnikova S, Martindale W, Thomas N, Simon J, Slabas A, et al.
Acta Crystallogr D Biol Crystallogr . 2000 Feb; 56(Pt 1):86-8. PMID: 10666637
The NADP-dependent beta-keto acyl-carrier protein reductase (BKR) from Brassica napus has been crystallized by the hanging-drop vapour-diffusion method using polyethylene glycol of average molecular weight 1500 as the precipitant. The...