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J B Hilliard

Explore the profile of J B Hilliard including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 429
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Recent Articles
1.
Chmiel J, Konstan M, Knesebeck J, Hilliard J, Bonfield T, Dawson D, et al.
Am J Respir Crit Care Med . 1999 Dec; 160(6):2040-7. PMID: 10588626
Cystic fibrosis (CF) lung disease is characterized by an excessive inflammatory response associated with chronic Pseudomonas aeruginosa endobronchial infection. Compared with bronchoalveolar lavage fluid from healthy subjects, lavage fluid from...
2.
Bonfield T, Panuska J, Konstan M, Hilliard K, Hilliard J, Ghnaim H, et al.
Am J Respir Crit Care Med . 1995 Dec; 152(6 Pt 1):2111-8. PMID: 8520783
Chronic pulmonary infection with Pseudomonas aeruginosa continues to be the major cause of morbidity and mortality in cystic fibrosis (CF). Several characteristics of CF, including the excessive influx of neutrophils...
3.
Bonfield T, Konstan M, Burfeind P, Panuska J, Hilliard J, Berger M
Am J Respir Cell Mol Biol . 1995 Sep; 13(3):257-61. PMID: 7544594
Interleukin-10 (IL-10) is a potent regulatory cytokine that decreases inflammatory responses and T-cell stimulation. We have found that respiratory epithelial lining fluid (ELF) from patients with cystic fibrosis (CF) contains...
4.
Konstan M, Walenga R, Hilliard K, Hilliard J
Am Rev Respir Dis . 1993 Oct; 148(4 Pt 1):896-901. PMID: 8214945
Persistent neutrophil infiltration into the airways of patients with cystic fibrosis (CF) results in lung destruction. Eicosanoid lipid mediators, particularly leukotriene B4 (LTB4), may play a role in neutrophil influx...
5.
Apseloff G, Hilliard J, Gerber N, Mays D
Xenobiotica . 1991 Nov; 21(11):1461-71. PMID: 1763520
1. Hexobarbital (100 mg/kg i.p.) sleeping times in male CD-1 mice pretreated (-1 h) with a single i.p. injection of 150 mumol/kg of psoralen or coumarin analogues were increased, most...
6.
Mays D, Hilliard J, Wong D, Chambers M, Park S, Gelboin H, et al.
J Pharmacol Exp Ther . 1990 Aug; 254(2):720-31. PMID: 2117068
The in vitro bioactivation of 8-MOP was studied in liver microsomes of male CD-1 mice. In 10-min incubations with 40 microM [14C]8-MOP, covalent binding (mean +/- S.D.) was 1.8 +/-...
7.
Mays D, Hilliard J, Wong D, Gerber N
Biochem Pharmacol . 1989 May; 38(10):1647-55. PMID: 2730678
The kinetics of covalent binding of reactive metabolites of 8-methoxypsoralen (8-MOP) to protein were measured in incubations of liver microsomes of rats pretreated for 3 days with i.p. injections of...
8.
Mays D, Nawoot S, Hilliard J, Pacula C, Gerber N
J Pharmacol Exp Ther . 1987 Oct; 243(1):227-33. PMID: 3668854
The effects of 8-methoxypsoralen (8-MOP) on drug metabolism in vivo were studied in catheterized rats. Rats were pretreated with a single i.p. injection of 5.4 or 27 mg/kg of 8-MOP,...