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J Arunakaran

Explore the profile of J Arunakaran including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 79
Citations 851
Followers 0
Related Specialties
Biochemistry
Endocrinology
Toxicology
Top 10 Co-Authors
M M Aruldhas
N Srinivasan
P Govindarajulu
K Balasubramanian
P Venkataraman
G Krishnamoorthy
A Arunkumar
R R Maran
P Kanagaraj
P Elumalai
Published In
Endocr Res
Indian J Exp Biol
Int J Androl
Hum Exp Toxicol
Biochem Mol Biol Int
Affiliations
Soon will be listed here.
Recent Articles
1.
Measurement of γ-H2AX foci, miRNA-101, and gene expression as a means to quantify radiation-absorbed dose in cancer patients who had undergone radiotherapy
Raavi V, Surendran J, Karthik K, Paul S, Thayalan K, Arunakaran J, et al.
Radiat Environ Biophys . 2018 Nov; 58(1):69-80. PMID: 30467642
Radiological accidents and nuclear terrorism pose an increased threat to members of the public who, following such an event, would need to be assessed for medical care by fast triage....
2.
Impact of Lactational Exposure to Polychlorinated Biphenyl Causes Epigenetic Modification and Impairs Sertoli Cells Functional Regulators in F Progeny
Priya E, Kumar T, Singh P, Balakrishnan S, Arunakaran J
Reprod Sci . 2017 Apr; 25(6):818-829. PMID: 28359186
Polychlorinated biphenyl (PCB) is an endocrine-disrupting chemical. Sertoli cells (SCs) provide physical and nutritional support for developing germ cells. Dysfunction in SCs has adverse effects on spermatogenesis. Previously, we found...
3.
Nimbolide inhibits androgen independent prostate cancer cells survival and proliferation by modulating multiple pro-survival signaling pathways
Singh P, Priya E, Balakrishnan S, Arunkumar R, Sharmila G, Rajalakshmi M, et al.
Biomed Pharmacother . 2016 Nov; 84:1623-1634. PMID: 27889231
Background: Prostate cancer is the most prominent cancer in men, experiencing a relapse in disease often express high serum TNF-α levels. It has been correlated with increased cell survival and...
4.
Neuroprotective Effect of Melatonin Against PCBs Induced Behavioural, Molecular and Histological Changes in Cerebral Cortex of Adult Male Wistar Rats
Bavithra S, Selvakumar K, Sundareswaran L, Arunakaran J
Neurochem Res . 2016 Nov; 42(2):428-438. PMID: 27804010
There is ample evidence stating Polychlorinated biphenyls (PCBs) as neurotoxins. In the current study, we have analyzed the behavioural impact of PCBs exposure in adult rats and assessed the simultaneous...
5.
Lactational exposure of polychlorinated biphenyls downregulates critical genes in Leydig cells of F1 male progeny (PND21)
Kumar T, Priya E, Singh P, Arunakaran J
Andrologia . 2016 Oct; 49(8). PMID: 27785823
Polychlorinated biphenyls (PCBs) are environmental contaminants. The present study was aimed to test the effect of lactational exposure of PCBs on Leydig cellular mRNA and protein expressions of 5α-reductase, aromatase...
6.
Gold nanoparticle-conjugated quercetin inhibits epithelial-mesenchymal transition, angiogenesis and invasiveness via EGFR/VEGFR-2-mediated pathway in breast cancer
Balakrishnan S, Bhat F, Singh P, Mukherjee S, Elumalai P, Das S, et al.
Cell Prolif . 2016 Sep; 49(6):678-697. PMID: 27641938
Objectives: Epidermal growth factor plays a critical role in breast malignancies by enhancing cell proliferation, invasion, angiogenesis and metastasis. Epithelial-mesenchymal transition (EMT) is a crucial process by which epithelial cells...
7.
Lactational exposure effect of polychlorinated biphenyl on rat Sertoli cell markers and functional regulators in prepuberal and puberal F offspring
Priya E, Kumar T, Balaji S, Bavithra S, Singh P, Sakthivel D, et al.
J Endocrinol Invest . 2016 Sep; 40(1):91-100. PMID: 27614457
Purpose: Polychlorinated biphenyls (PCBs) are persistent and bioaccumulative environmental toxicants acting as endocrine disruptors. Many researches evidenced that PCBs affect the male reproductive system in adult rats and it can...
8.
Effect of Melatonin on Glutamate: BDNF Signaling in the Cerebral Cortex of Polychlorinated Biphenyls (PCBs)-Exposed Adult Male Rats
Bavithra S, Priya E, Selvakumar K, Krishnamoorthy G, Arunakaran J
Neurochem Res . 2015 Jul; 40(9):1858-69. PMID: 26224288
Various epidemiological survey suggests that the central nervous system is the target for many environmental contaminants. One among them is Aroclor 1254, a mixture of polychlorinated biphenyls (PCBs) which explore...
9.
Nimbolide inhibits invasion and migration, and down-regulates uPAR chemokine gene expression, in two breast cancer cell lines
Elumalai P, Brindha Mercy A, Arunkamar R, Sharmila G, Bhat F, Balakrishnan S, et al.
Cell Prolif . 2014 Nov; 47(6):540-52. PMID: 25377085
Objectives: Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women, worldwide. Urokinase type plasminogen activator (uPA) is a serine protease that is...
10.
Quercetin, a natural dietary flavonoid, acts as a chemopreventive agent against prostate cancer in an in vivo model by inhibiting the EGFR signaling pathway
Firdous A, Sharmila G, Balakrishnan S, Rajasingh P, Suganya S, Srinivasan N, et al.
Food Funct . 2014 Aug; 5(10):2632-45. PMID: 25164625
Prostate cancer incidence and mortality rates have increased over the past years. The purpose of the present study was to examine the molecular mechanism underlying the chemopreventive effects of quercetin...