J Arunakaran

Overview

Explore the profile of J Arunakaran including associated specialties, affiliations and a list of published articles.

Snapshot

Articles 79

Citations 851

Followers 0

Related Specialties

Biochemistry

Endocrinology

Toxicology

Top 10 Co-Authors

M M Aruldhas

N Srinivasan

P Govindarajulu

K Balasubramanian

P Venkataraman

G Krishnamoorthy

A Arunkumar

R R Maran

P Kanagaraj

P Elumalai

Published In

Endocr Res

Indian J Exp Biol

Int J Androl

Hum Exp Toxicol

Biochem Mol Biol Int

Affiliations

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Recent Articles

11.

Quercetin reverses EGF-induced epithelial to mesenchymal transition and invasiveness in prostate cancer (PC-3) cell line via EGFR/PI3K/Akt pathway

Bhat F, Sharmila G, Balakrishnan S, Arunkumar R, Elumalai P, Suganya S, et al.

J Nutr Biochem . 2014 Aug; 25(11):1132-1139. PMID: 25150162

Epidermal growth factor (EGF) plays an important role in metastasis and tumorigenesis of prostate cancer. Epithelial-mesenchymal transition (EMT) is a process in tumor progression during which cancer cells undergo dramatic...

12.

Chemopreventive effect of quercetin, a natural dietary flavonoid on prostate cancer in in vivo model

Sharmila G, Bhat F, Arunkumar R, Elumalai P, Singh P, Senthilkumar K, et al.

Clin Nutr . 2013 Oct; 33(4):718-26. PMID: 24080313

Background & Aim: Prostate cancer is one of the frequently diagnosed cancers in men. Increased Growth factor IGF-1/IGF-1R axis activation mediated by both PI3K/Akt or RAF/MEK/ERK system and AR expression...

13.

Polychlorinated biphenyls induced oxidative stress mediated neurodegeneration in hippocampus and behavioral changes of adult rats: anxiolytic-like effects of quercetin

Selvakumar K, Bavithra S, Ganesh L, Krishnamoorthy G, Venkataraman P, Arunakaran J

Toxicol Lett . 2013 Jul; 222(1):45-54. PMID: 23831945

Polychlorinated biphenyls (PCBs) are extremely toxic environmental contaminant speculated to accelerate neurochemical and behavioral damages. Developmental and behavioral development relies on the proper functioning of the endogenous neurotransmitters that remain...

14.

Anti-cancer activity of quercetin in neuroblastoma: an in vitro approach

Priya E, Selvakumar K, Bavithra S, Elumalai P, Arunkumar R, Singh P, et al.

Neurol Sci . 2013 Jun; 35(2):163-70. PMID: 23771516

Neuroblastoma is a neuroendocrine tumour derived from neural crest cells and it remains a major therapeutic challenge in pediatric oncology. As response rates to chemotherapy are low, surgery remains the...

15.

Melatonin attenuates polychlorinated biphenyls induced apoptosis in the neuronal cells of cerebral cortex and cerebellum of adult male rats--in vivo

Bavithra S, Selvakumar K, Krishnamoorthy G, Venkataraman P, Arunakaran J

Environ Toxicol Pharmacol . 2013 Apr; 36(1):152-63. PMID: 23619521

Polychlorinated biphenyls (PCBs) are widespread persistent environmental contaminants that display a complex spectrum of toxicological properties, including neurotoxicity. Studies have shown that PCBs increase oxidative stress in brain, leading to...

16.

Polychlorinated biphenyls impair blood-brain barrier integrity via disruption of tight junction proteins in cerebrum, cerebellum and hippocampus of female Wistar rats: neuropotential role of quercetin

Selvakumar K, Prabha R, Saranya K, Bavithra S, Krishnamoorthy G, Arunakaran J

Hum Exp Toxicol . 2012 Nov; 32(7):706-20. PMID: 23155198

Polychlorinated biphenyls (PCBs) comprise a ubiquitous class of toxic substances associated with carcinogenic and tumor-promoting effects as well as neurotoxic properties. Reactive oxygen species, which is produced from PCBs, alters...

17.

Induction of apoptosis in human breast cancer cells by nimbolide through extrinsic and intrinsic pathway

Elumalai P, Gunadharini D, Senthilkumar K, Banudevi S, Arunkumar R, Benson C, et al.

Toxicol Lett . 2012 Oct; 215(2):131-42. PMID: 23089555

We aimed to investigate the cytotoxic effects of nimbolide, a limonoid present in leaves and flowers of the neem tree (Azadirachta indica) on human breast cancer cells. The molecular mechanisms...

18.

Di 2-ethyl hexyl phthalate affects differentiation and matrix mineralization of rat calvarial osteoblasts--in vitro

Bhat F, Ramajayam G, Parameswari S, Vignesh R, Karthikeyan S, Senthilkumar K, et al.

Toxicol In Vitro . 2012 Sep; 27(1):250-6. PMID: 22985736

Di-2-ethyl hexyl phthalate (DEHP), an industrial plasticizer and a ubiquitous environmental contaminant, is an established endocrine disruptor (ED). Increasing evidences indicate that some EDs interfere with osteoblast differentiation and function....

19.

Effect of diallyl disulfide on insulin-like growth factor signaling molecules involved in cell survival and proliferation of human prostate cancer cells in vitro and in silico approach through docking analysis

Arunkumar R, Sharmila G, Elumalai P, Senthilkumar K, Banudevi S, Gunadharini D, et al.

Phytomedicine . 2012 Jun; 19(10):912-23. PMID: 22739413

Purpose: Diallyl Disulfide (DADS) is one of the major components of garlic, which inhibits the proliferation of various cancer cells. Our previous studies showed that DADS inhibits cell growth and...

20.

Regulation of insulin-like growth factors and their binding proteins by thyroid stimulating hormone in human osteoblast-like (SaOS2) cells

Ramajayam G, Vignesh R, Karthikeyan S, Senthil Kumar K, Karthikeyan G, Veni S, et al.

Mol Cell Biochem . 2012 Jun; 368(1-2):77-88. PMID: 22673962

Thyroid stimulating hormone (TSH) is shown to have definite anabolic effects on skeletal metabolism. Previous studies have demonstrated that Insulin-like growth factors (IGF-I and IGF-II) and their six high affinity...