J A McCloskey
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Explore the profile of J A McCloskey including associated specialties, affiliations and a list of published articles.
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148
Citations
3015
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Recent Articles
1.
Pomerantz S, Kowalak J, McCloskey J
J Am Soc Mass Spectrom
. 2013 Nov;
4(3):204-9.
PMID: 24234848
Extensive calculations for molecular mass versus subunit composition have been made for oligonucleotides from RNA and DNA to determine the extent to which base compositions might be derived from mass...
2.
Nelson C, McCloskey J
J Am Soc Mass Spectrom
. 2013 Nov;
5(5):339-49.
PMID: 24222588
The collision-induced dissociation of protonated uracil has been studied by tandem mass spectrometry using models extensively labeled with stable isotopes, and derivatives of the kinds found in nucleic acids. Following...
3.
Limbach P, Crain P, McCloskey J
J Am Soc Mass Spectrom
. 2013 Nov;
6(1):27-39.
PMID: 24222058
The use of electrospray ionization mass spectrometry for the accurate determination of molecular masses of polynucleotides and small nucleic acids is developed. The common problem of gas phase cation adduction...
4.
Posttranscriptional modification of transfer RNA in the submarine hyperthermophile Pyrolobus fumarii
McCloskey J, Liu X, Crain P, BRUENGER E, Guymon R, Hashizume T, et al.
Nucleic Acids Symp Ser
. 2003 Aug;
(44):267-8.
PMID: 12903371
In the RNA of hyperthermophiles, which grow optimally between 80 degrees C and 106 degrees C, posttranscriptional modification has been identified as a leading mechanism of structural stabilization. Particularly in...
5.
McCloskey J, Graham D, Zhou S, Crain P, Ibba M, Konisky J, et al.
Nucleic Acids Res
. 2001 Nov;
29(22):4699-706.
PMID: 11713320
Post-transcriptional modifications in archaeal RNA are known to be phylogenetically distinct but relatively little is known of tRNA from the Methanococci, a lineage of methanogenic marine euryarchaea that grow over...
6.
Kowalak J, BRUENGER E, Crain P, McCloskey J
J Biol Chem
. 2000 May;
275(32):24484-9.
PMID: 10818097
Small subunit (16 S) rRNA from the archaeon Haloferax volcanii, for which sites of modification were previously reported, was examined using mass spectrometry. A census of all modified residues was...
7.
Tomita K, Ueda T, Ishiwa S, Crain P, McCloskey J, Watanabe K
Nucleic Acids Res
. 1999 Oct;
27(21):4291-7.
PMID: 10518623
Mitochondrial (mt) tRNA(Trp), tRNA(Ile), tRNA(Met), tRNA(Ser)GCU, tRNA(Asn)and tRNA(Lys)were purified from Drosophila melanogaster (fruit fly) and their nucleotide sequences were determined. tRNA(Lys)corresponding to both AAA and AAG lysine codons was found...
8.
McCloskey J, Whitehill A, Rozenski J, Qiu F, Crain P
Nucleosides Nucleotides
. 1999 Sep;
18(6-7):1549-53.
PMID: 10474232
Recent advances in combined HPLC/electrospray ionization-mass spectrometry provide effective new capabilities for the rapid characterization of oligonucleotides. Accurate mass measurements with errors < 0.3 Da, and determination of base and...
9.
Qiu F, McCloskey J
Nucleic Acids Res
. 1999 Sep;
27(18):e20.
PMID: 10471750
Post-transcriptional methylation of ribose at position O-2' is one of the most common and conserved types of RNA modification. Details of the functional roles of these methylations are far from...
10.
Rozenski J, McCloskey J
Anal Chem
. 1999 Apr;
71(7):1454-9.
PMID: 10204043
The identification of nearest-neighbor residues in nucleic acids provides useful constraints on establishment of base composition and sequence and is potentially applicable to a range of structural problems involving synthetic...