J A Hata
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Explore the profile of J A Hata including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
179
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Recent Articles
1.
Pleger S, Most P, Heidt B, Voelkers M, Hata J, Katus H, et al.
Eur J Med Res
. 2006 Nov;
11(10):418-22.
PMID: 17107875
S100A1, a Ca superset2+-binding protein of the EF-hand type, is preferentially expressed in myocardial tissue and has been shown to enhance cardiac contractile performance by regulating both sarcoplasmic reticulum (SR)...
2.
Shah A, White D, Tai O, Hata J, WILSON K, Pippen A, et al.
J Thorac Cardiovasc Surg
. 2000 Aug;
120(3):581-8.
PMID: 10962422
Objectives: Ex vivo perfusion of the cardiac allograft during organ procurement is an ideal environment for adenoviral vectors with transgenes that target improving graft contractility. One such target is the...
3.
Shah A, Atkins B, Hata J, Tai O, Kypson A, Lilly R, et al.
J Thorac Cardiovasc Surg
. 2000 Aug;
120(2):342-9.
PMID: 10917952
Objective: Right ventricular dysfunction is a poorly understood but persistent clinical problem. This study was undertaken to evaluate ventricular performance and beta-adrenergic receptor signaling in a tricuspid regurgitation model of...
4.
White D, Hata J, Shah A, Glower D, Lefkowitz R, Koch W
Proc Natl Acad Sci U S A
. 2000 Apr;
97(10):5428-33.
PMID: 10779554
When the heart fails, there is often a constellation of biochemical alterations of the beta-adrenergic receptor (betaAR) signaling system, leading to the loss of cardiac inotropic reserve. betaAR down-regulation and...
5.
Shah A, Lilly R, Kypson A, Tai O, Hata J, Pippen A, et al.
Circulation
. 2000 Feb;
101(4):408-14.
PMID: 10653833
Background: Genetic modulation of ventricular function may offer a novel therapeutic strategy for patients with congestive heart failure. Myocardial overexpression of beta(2)-adrenergic receptors (beta(2)ARs) has been shown to enhance contractility...
6.
Maurice J, Hata J, Shah A, White D, McDonald P, Dolber P, et al.
J Clin Invest
. 1999 Jul;
104(1):21-9.
PMID: 10393695
Exogenous gene delivery to alter the function of the heart is a potential novel therapeutic strategy for treatment of cardiovascular diseases such as heart failure (HF). Before gene therapy approaches...
7.
Maurice J, Shah A, Kypson A, Hata J, White D, Glower D, et al.
Am J Physiol
. 1999 Jun;
276(6):H1853-60.
PMID: 10362663
We studied alterations in the beta-adrenergic receptor (beta-AR) system of rabbit hearts during the development of heart failure (HF) after myocardial infarction (MI) to determine whether the molecular beta-AR abnormalities...