J A Hardy
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Explore the profile of J A Hardy including associated specialties, affiliations and a list of published articles.
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87
Citations
3444
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Recent Articles
1.
Hardy J, Wester P, Backstrom I, Gottfries J, Oreland L, Stenstrom A, et al.
Neurochem Int
. 2010 May;
10(4):445-50.
PMID: 20501116
The regional distribution of the dopamine and serotonin uptake sites in human brain have been assessed and compared with the distribution of the transmitters and their metabolites measured in the...
2.
Cowburn R, Dodd P, Hardy J, Johnston G
Neurochem Int
. 2010 May;
10(3):339-46.
PMID: 20501104
Synaptosomes were prepared from frozen post mortem human brain and from fresh rat brains. These preparations were used to compare the pharmacological properties of the sodium dependent, high affinity, excitatory...
3.
McDermott J, Dodd P, Edwardson J, Hardy J, Smith A
Neurochem Int
. 2010 May;
5(5):641-7.
PMID: 20487993
Cholecystokinin octapeptide (CCK-8) was degraded by peptidases present in intact synaptosomes isolated from rat cortex and hypothalamus. Most of the degrading activity was present in the cytoplasmic fraction although a...
4.
Hardy J, Dodd P
Neurochem Int
. 2010 May;
5(3):253-66.
PMID: 20487948
The evidence that samples of human brain tissue obtained at autopsy may be used as starting material for the isolation of cellular and subcellular preparations which exhibit metabolic and functional...
5.
Wiklund P, Brown W, Brott T, Stegmayr B, Brown Jr R, Nilsson-Ardnor S, et al.
Neurology
. 2007 Feb;
68(6):427-31.
PMID: 17283317
Objective: To establish whether subtypes of ischemic stroke aggregate within ischemic stroke-affected sibling pairs more than expected by chance alone. Methods: This retrospective family study was based on a pooled...
6.
Meschia J, Brott T, Brown Jr R, Kissela B, Hardy J, Brown W, et al.
Neurology
. 2005 Mar;
64(6):1061-3.
PMID: 15781828
The authors found a correlation between the age at which probands experience an incident stroke and the age at which their siblings experience an incident stroke (r = 0.68; p...
7.
Busby J, OBrien K, Gibson A, McKeith I, Perry R, Hardy J, et al.
Neurogenetics
. 2004 Oct;
5(4):251-2.
PMID: 15490287
No abstract available.
8.
Maraganore D, Hernandez D, Singleton A, Farrer M, McDonnell S, Hutton M, et al.
Ann Neurol
. 2001 Nov;
50(5):658-61.
PMID: 11706972
We investigated the association of Parkinson's disease with tau gene haplotypes. In a sample of 319 unrelated Parkinson's disease patients and 196 control subjects, we observed an increased risk of...
9.
Hardy J, NELSON H
Protein Sci
. 2001 Apr;
9(11):2128-41.
PMID: 11305238
The DNA-binding domain of the yeast heat shock transcription factor (HSF) contains a strictly conserved proline that is at the center of a kink. To define the role of this...
10.
Cicero M, HUBL S, Harrison C, Littlefield O, Hardy J, NELSON H
Nucleic Acids Res
. 2001 Apr;
29(8):1715-23.
PMID: 11292844
The yeast heat shock transcription factor (HSF) belongs to the winged helix family of proteins. HSF binds DNA as a trimer, and additional trimers can bind DNA co-operatively. Unlike other...