J A Frelinger
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Explore the profile of J A Frelinger including associated specialties, affiliations and a list of published articles.
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161
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2201
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Recent Articles
1.
Nixon D, Ting J, Frelinger J
Immunol Today
. 2014 Oct;
3(12):339-42.
PMID: 25290677
Ia molecules are encoded in the 1 region of the mouse major histocompatibility complex (MIX) and expressed as surface antigens on certain immunologically active cells (reviewed in Ref. 1). B...
2.
Phillippi J, Xie Y, Miller D, Bell T, Zhang Z, Lenarcic A, et al.
Genes Immun
. 2013 Nov;
15(1):38-46.
PMID: 24195963
The Collaborative Cross (CC) is an emerging panel of recombinant inbred (RI) mouse strains. Each strain is genetically distinct but all descended from the same eight inbred founders. In 66...
3.
Ross P, Buntzman A, Vincent B, Grover E, Gojanovich G, Collins E, et al.
Tissue Antigens
. 2012 May;
80(2):175-83.
PMID: 22571293
In the dog, previous analyses of major histocompatibility complex class I genes suggest a single polymorphic locus, dog leukocyte antigen (DLA)-88. While 51 alleles have been reported, estimates of prevalence...
4.
Maizels R, Frelinger J, Hood L
Immunogenetics
. 2011 Feb;
7(1):425-44.
PMID: 21302097
The partial N-terminal amino acid sequences of the K and D gene products from theH-2 ( q ) andH-2 ( s ) haplotypes are presented. These data in conjunction with...
5.
Zhang T, Jin D, Wardrop 3rd R, Gui T, Maile R, Frelinger J, et al.
Gene Ther
. 2006 Oct;
14(5):429-40.
PMID: 17066096
Immune responses leading to antibody-mediated elimination of the transgenic protein are a concern in gene replacement for congenital protein deficiencies, for which hemophilia is an important model. Although most hemophilia...
6.
Greenwood R, Wang B, Midkiff K, White 2nd G, Lin H, Frelinger J
J Thromb Haemost
. 2003 Jul;
1(1):95-102.
PMID: 12871545
Immune responses to the factor IX protein pose problems for hemophilia B patients who develop antibodies against factor IX and for potential future treatment with gene therapy. To better define...
7.
Gerber S, MORAN J, Frelinger J, Frelinger J, Fenton B, Lord E
Br J Cancer
. 2003 Jun;
88(9):1453-61.
PMID: 12778077
New blood vessel formation within tumours is a critical feature for tumour growth. A major limitation in understanding this complex process has been the inability to visualise and analyse vessel...
8.
Garba M, Frelinger J
J Immunol Methods
. 2001 Oct;
258(1-2):193-8.
PMID: 11684136
TGF-beta is a well-described immunoregulatory molecule that is produced by most cell types. Many studies have been aimed at investigating the role played by TGF-beta in different cell types and...
9.
Abdel-Motal U, Friedline R, Poligone B, Frelinger J, Tisch R
Clin Immunol
. 2001 Oct;
101(1):51-8.
PMID: 11580226
Dendritic cells (DC) are highly efficient at inducing primary T cell responses. Consequently, DC are being investigated for their potential to prevent and/or treat human immunodeficiency virus type 1 (HIV-1)...
10.
Maile R, Wang B, Schooler W, Meyer A, Collins E, Frelinger J
J Immunol
. 2001 Sep;
167(7):3708-14.
PMID: 11564786
Soluble MHC/peptide tetramers that can directly bind the TCR allow the direct visualization and quantitation of Ag-specific T cells in vitro and in vivo. We used HY-D(b) tetramers to assess...