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J-C Bourdon

Explore the profile of J-C Bourdon including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 920
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Recent Articles
1.
Mao X, Gauche C, Coughtrie M, Bui C, Gulberti S, Merhi-Soussi F, et al.
Oncogene . 2016 Apr; 35(38):5043-55. PMID: 27041583
Heparan sulfate (HS) proteoglycan chains are key components of the breast tumor microenvironment that critically influence the behavior of cancer cells. It is established that abnormal synthesis and processing of...
2.
Marcel V, Fernandes K, Terrier O, Lane D, Bourdon J
Cell Death Differ . 2014 Jun; 21(9):1377-87. PMID: 24926616
In addition to the tumor suppressor p53 protein, also termed p53α, the TP53 gene produces p53β and p53γ through alternative splicing of exons 9β and 9γ located within TP53 intron...
3.
Dichtel-Danjoy M, Ma D, Dourlen P, Chatelain G, Napoletano F, Robin M, et al.
Cell Death Differ . 2012 Aug; 20(1):108-16. PMID: 22898807
Irradiated or injured cells enter apoptosis, and in turn, promote proliferation of surrounding unaffected cells. In Drosophila, apoptotic cells have an active role in proliferation, where the caspase Dronc and...
4.
Allende-Vega N, Dayal S, Agarwala U, Sparks A, Bourdon J, Saville M
Oncogene . 2012 Feb; 32(1):1-14. PMID: 22349816
In this study, we show that interfering with the splicing machinery results in activation of the tumour-suppressor p53. The spliceosome was targeted by small interfering RNA-mediated knockdown of proteins associated...
5.
Marcel V, Petit I, Murray-Zmijewski F, Goullet de Rugy T, Fernandes K, Meuray V, et al.
Cell Death Differ . 2011 Nov; 19(5):816-26. PMID: 22075982
In response to stress, p53 binds and transactivates the internal TP53 promoter, thus regulating the expression of its own isoform, Δ133p53α. Here, we report that, in addition to p53, at...
6.
Marcel V, Dichtel-Danjoy M, Sagne C, Hafsi H, Ma D, Ortiz-Cuaran S, et al.
Cell Death Differ . 2011 Sep; 18(12):1815-24. PMID: 21941372
The TP53 tumour-suppressor gene is expressed as several protein isoforms generated by different mechanisms, including use of alternative promoters, splicing sites and translational initiation sites, that are conserved through evolution...
7.
Anensen N, Hjelle S, Van Belle W, Haaland I, Silden E, Bourdon J, et al.
Oncogene . 2011 Aug; 31(12):1533-45. PMID: 21860418
The wild-type tumor-suppressor gene TP53 encodes several isoforms of the p53 protein. However, while the role of p53 in controlling normal cell cycle progression and tumor suppression is well established,...
8.
Watt S, Pourreyron C, Purdie K, Hogan C, Cole C, Foster N, et al.
Oncogene . 2011 May; 30(46):4666-77. PMID: 21602893
Identifying therapeutic targets for cancer treatment relies on consistent changes within particular types or sub-types of malignancy. The ability to define either consistent changes or sub-types of malignancy is often...
9.
Dalvai M, Mondesert O, Bourdon J, Ducommun B, Dozier C
Oncogene . 2011 Jan; 30(19):2282-8. PMID: 21242964
Cdc25B phosphatases function as key players in G2/M cell cycle progression by activating the CDK1-cyclinB1 complexes. They also have an essential role in recovery from the G2/M checkpoint activated in...
10.
Marcel V, Olivier M, Mollereau B, Hainaut P, Bourdon J
Cell Death Differ . 2010 Dec; 18(3):563-4. PMID: 21151028
No abstract available.