Izabela Podgorski
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Explore the profile of Izabela Podgorski including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Garmo L, Herroon M, Mecca S, Wilson A, Allen D, Agarwal M, et al.
Toxicol Appl Pharmacol
. 2024 Aug;
491:117047.
PMID: 39111555
Per- and polyfluoroalkyl substances (PFAS) bioaccumulate in different organ systems, including bone. While existing research highlights the adverse impact of PFAS on bone density, a critical gap remains in understanding...
2.
Denison M, Ullrich A, Herroon M, Mecca S, Turro C, Podgorski I, et al.
bioRxiv
. 2024 Aug;
PMID: 39091867
Immunotherapy has emerged as a promising avenue for cancer treatment by bolstering the immune system's ability to recognize and attack cancer cells. Photodynamic therapy shows potential in enhancing antitumor immunity,...
3.
Morse P, Wan J, Arroum T, Herroon M, Kalpage H, Bazylianska V, et al.
Biomolecules
. 2024 Jun;
14(6).
PMID: 38927098
Cytochrome (Cyt) is important for both mitochondrial respiration and apoptosis, both of which are altered in cancer cells that switch to Warburg metabolism and manage to evade apoptosis. We earlier...
4.
Denison M, Garcia S, Ullrich A, Podgorski I, Gibson H, Turro C, et al.
Inorg Chem
. 2024 Apr;
63(17):7973-7983.
PMID: 38616353
Dysregulated cathepsin activity is linked to various human diseases including metabolic disorders, autoimmune conditions, and cancer. Given the overexpression of cathepsin in the tumor microenvironment, cathepsin inhibitors are promising pharmacological...
5.
Heravi G, Liu Z, Herroon M, Wilson A, Fan Y, Jiang Y, et al.
bioRxiv
. 2024 Apr;
PMID: 38586033
Monounsaturated fatty acids (MUFAs) play a pivotal role in maintaining endoplasmic reticulum (ER) homeostasis, an emerging hallmark of cancer. However, the role of polyunsaturated fatty acid (PUFAs) desaturation in persistent...
6.
Beebe-Dimmer J, Finlay D, Ruterbusch J, Baird T, Simon M, Abrams J, et al.
Prev Med Rep
. 2023 Jul;
35:102288.
PMID: 37449003
Purpose: Given the well-documented benefits of regular exercise to cancer survivors, current American Cancer Society guidelines recommend that patients engage in a minimum of 150 min per week of moderate-to-vigorous...
7.
Hazelton J, Kim S, Boerner J, Podgorski I, Perk T, Cackowski F, et al.
Prostate
. 2023 May;
83(12):1193-1200.
PMID: 37211866
Background: Bone is the most common site of metastases in men with prostate cancer. The objective of this study was to explore potential racial differences in the distribution of tumor...
8.
Wilson A, Garmo L, Podgorski I
Pharmacol Ther
. 2022 Aug;
238:108274.
PMID: 36038018
Bone is a frequent site of metastasis from several organs and a host for cancer cells that have originated from the bone marrow itself. Skeletal malignancies are extremely difficult to...
9.
Toupin N, Herroon M, Thummel R, Turro C, Podgorski I, Gibson H, et al.
Chemistry
. 2022 Mar;
28(24):e202104430.
PMID: 35235227
Tumor associated macrophages (TAMs) suppress the cancer immune response and are a key target for immunotherapy. The effects of ruthenium and rhodium complexes on TAMs have not been well characterized....
10.
Toupin N, Steinke S, Herroon M, Podgorski I, Turro C, Kodanko J
Photochem Photobiol
. 2021 Dec;
98(2):378-388.
PMID: 34866185
We report the synthesis, photochemical and biological characterization of two new Ru(II) photoactivated complexes based on [Ru(tpy)(Me bpy)(L)] (tpy = 2,2':6',2''-terpyridine, Me bpy = 6,6'-dimethyl-2,2'-bipyridine), where L = pyridyl-BODIPY (pyBOD)....