Ivana Celardo
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Explore the profile of Ivana Celardo including associated specialties, affiliations and a list of published articles.
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20
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Recent Articles
1.
Collen E, Bartmann K, Blum J, Carstens K, Celardo I, Chatterjee N, et al.
ALTEX
. 2025 Jan;
PMID: 39826153
On occasion of the DNT5 meeting in Konstanz, Germany (April-2024), participants brainstormed on future challenges concerning a regulatory implementation of the developmental neurotoxicity (DNT) in vitro test battery (DNT-IVB). The...
2.
Brull M, Multrus S, Schafer M, Celardo I, Karreman C, Leist M
Cell Death Dis
. 2025 Jan;
16(1):24.
PMID: 39824831
Neurite degeneration (ND) precedes cell death in many neurodegenerative diseases. However, it remains unclear how this compartmentalized cell death process is orchestrated in the central nervous system (CNS). The establishment...
3.
Caporali S, Butera A, Ruzza A, Zampieri C, Bantula M, Scharsich S, et al.
J Exp Clin Cancer Res
. 2024 Nov;
43(1):310.
PMID: 39587609
Background: Approximately half of all human cancers harbour mutations in the p53 gene, leading to the generation of neomorphic p53 mutant proteins. These mutants can exert gain-of-function (GOF) effects, potentially...
4.
Yu Y, Chen C, Celardo I, Tan B, Hurcomb J, Leal N, et al.
Cell Death Dis
. 2024 Nov;
15(11):856.
PMID: 39582067
Alzheimer's disease (AD) is the most common form of age-related dementia. In AD, the death of neurons in the central nervous system is associated with the accumulation of toxic amyloid...
5.
Brull M, Geese N, Celardo I, Laumann M, Leist M
Cells
. 2024 Feb;
13(3.
PMID: 38334634
Few models allow the study of neurite damage in the human central nervous system. We used here dopaminergic LUHMES neurons to establish a culture system that allows for (i) the...
6.
Suciu I, Delp J, Gutbier S, Suess J, Henschke L, Celardo I, et al.
Antioxidants (Basel)
. 2024 Jan;
13(1).
PMID: 38247474
To characterize the hits from a phenotypic neurotoxicity screen, we obtained transcriptomics data for valinomycin, diethylstilbestrol, colchicine, rotenone, 1-methyl-4-phenylpyridinium (MPP), carbaryl and berberine (Ber). For all compounds, the concentration triggering...
7.
Fedele G, Loh S, Celardo I, Leal N, Lehmann S, Costa A, et al.
Nat Aging
. 2023 Apr;
2(4):317-331.
PMID: 37117744
The innate immune response mounts a defense against foreign invaders and declines with age. An inappropriate induction of this response can cause diseases. Previous studies showed that mitochondria can be...
8.
Suciu I, Delp J, Gutbier S, Uckert A, Spreng A, Eberhard P, et al.
Antioxidants (Basel)
. 2023 Jan;
12(1).
PMID: 36671027
Proteasome inhibition is associated with parkinsonian pathology in vivo and degeneration of dopaminergic neurons in vitro. We explored here the metabolome (386 metabolites) and transcriptome (3257 transcripts) regulations of human...
9.
Panatta E, Butera A, Celardo I, Leist M, Melino G, Amelio I
Biol Direct
. 2022 Dec;
17(1):38.
PMID: 36461070
Nuclear organisation and architecture are essential for the maintenance of genomic integrity as well as for the epigenetic regulations and gene expression. Disruption of lamin B1, major structural and functional...
10.
Yu Y, Fedele G, Celardo I, Loh S, Martins L
Cell Death Dis
. 2021 Jul;
12(8):720.
PMID: 34285196
No abstract available.