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Ivan R Nabi

Explore the profile of Ivan R Nabi including associated specialties, affiliations and a list of published articles. Areas
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Articles 81
Citations 6903
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Recent Articles
1.
Wong T, Khater I, Hallgrimson C, Li Y, Hamarneh G, Nabi I
J Cell Sci . 2025 Jan; 138(4). PMID: 39865933
SuperResNET is a network analysis pipeline for the analysis of point cloud data generated by single-molecule localization microscopy (SMLM). Here, we applied SuperResNET network analysis of SMLM direct stochastic optical...
2.
Nabi I, Cardoen B, Khater I, Gao G, Wong T, Hamarneh G
J Cell Biol . 2024 Jun; 223(8). PMID: 38865088
Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell, bridging the mesoscale gap to classical...
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Lim J, Bernatchez P, Nabi I
Biochem Soc Trans . 2024 Mar; 52(2):947-959. PMID: 38526159
Caveolin-1 (Cav1) is a 22 kDa intracellular protein that is the main protein constituent of bulb-shaped membrane invaginations known as caveolae. Cav1 can be also found in functional non-caveolar structures...
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Timmins L, Ortiz-Silva M, Joshi B, Li Y, Dickson F, Wong T, et al.
FASEB J . 2023 Dec; 38(1):e23343. PMID: 38071602
Caveolin-1 (CAV1), the main structural component of caveolae, is phosphorylated at tyrosine-14 (pCAV1), regulates signal transduction, mechanotransduction, and mitochondrial function, and plays contrasting roles in cancer progression. We report that...
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Cardoen B, Vandevoorde K, Gao G, Ortiz-Silva M, Alan P, Liu W, et al.
J Cell Biol . 2023 Nov; 223(1). PMID: 37948126
Identification and morphological analysis of mitochondria-ER contacts (MERCs) by fluorescent microscopy is limited by subpixel resolution interorganelle distances. Here, the membrane contact site (MCS) detection algorithm, MCS-DETECT, reconstructs subpixel resolution...
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Alan P, Vandevoorde K, Joshi B, Cardoen B, Gao G, Mohammadzadeh Y, et al.
Cell Mol Life Sci . 2022 Oct; 79(11):565. PMID: 36284011
Mitochondria are major sources of cytotoxic reactive oxygen species (ROS), such as superoxide and hydrogen peroxide, that when uncontrolled contribute to cancer progression. Maintaining a finely tuned, healthy mitochondrial population...
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Saberian M, Moriarty K, Olmstead A, Hallgrimson C, Jean F, Nabi I, et al.
IEEE Trans Med Imaging . 2022 May; 41(11):3128-3145. PMID: 35622798
Drug repurposing can accelerate the identification of effective compounds for clinical use against SARS-CoV-2, with the advantage of pre-existing clinical safety data and an established supply chain. RNA viruses such...
9.
Wong T, Khater I, Joshi B, Shahsavari M, Hamarneh G, Nabi I
Sci Rep . 2021 Apr; 11(1):7810. PMID: 33833286
Caveolin-1 (CAV1), the caveolae coat protein, also associates with non-caveolar scaffold domains. Single molecule localization microscopy (SMLM) network analysis distinguishes caveolae and three scaffold domains, hemispherical S2 scaffolds and smaller...
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Long R, Moriarty K, Cardoen B, Gao G, Vogl A, Jean F, et al.
Sci Rep . 2020 Dec; 10(1):20937. PMID: 33262363
The endoplasmic reticulum (ER) is a complex subcellular organelle composed of diverse structures such as tubules, sheets and tubular matrices. Flaviviruses such as Zika virus (ZIKV) induce reorganization of ER...