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Ivan J Stone

Explore the profile of Ivan J Stone including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 400
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11.
Oflazoglu E, Stone I, Gordon K, Grewal I, van Rooijen N, Law C, et al.
Blood . 2007 Oct; 110(13):4370-2. PMID: 17909075
Increased expression of CD30 is associated with a variety of hematologic malignancies, including Hodgkin disease (HD) and anaplastic large cell lymphoma (ALCL). The anti-CD30 monoclonal antibody SGN-30 induces direct antitumor...
12.
Jeffrey S, Andreyka J, Bernhardt S, Kissler K, Kline T, Lenox J, et al.
Bioconjug Chem . 2006 May; 17(3):831-40. PMID: 16704224
A beta-glucuronide-based linker for attaching cytotoxic agents to monoclonal antibodies (mAbs) was designed and evaluated. We employed the cytotoxic auristatin derivatives MMAE (1a) and MMAF (1b) and doxorubicin propyloxazoline (DPO,...