Iuliia Savchuk
Overview
Explore the profile of Iuliia Savchuk including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
123
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Recent Articles
1.
Wagner I, Savchuk I, Sahlin L, Kulle A, Kloting N, Dietrich A, et al.
Obes Facts
. 2022 Jan;
15(2):281-291.
PMID: 34983051
Introduction: Obesity in women is often associated with hyperandrogenism, but the role of adipose tissue (AT) in androgen synthesis remains unclear. Therefore, we studied whether AT could be a source...
2.
Wagner I, Kloting N, Savchuk I, Eifler L, Kulle A, Kralisch-Jacklein S, et al.
Endocrinology
. 2021 Jan;
162(4).
PMID: 33507237
Type 1 diabetes mellitus (T1DM) is associated with impaired spermatogenesis and lower testosterone levels and epididymal weight. However, the underlying processes in the testis are unknown and remain to be...
3.
OShaughnessy P, Antignac J, Le Bizec B, Morvan M, Svechnikov K, Soder O, et al.
PLoS Biol
. 2019 Feb;
17(2):e3000002.
PMID: 30763313
Masculinization of the external genitalia in humans is dependent on formation of 5α-dihydrotestosterone (DHT) through both the canonical androgenic pathway and an alternative (backdoor) pathway. The fetal testes are essential...
4.
Wagner I, Sahlin L, Savchuk I, Kloting N, Svechnikov K, Soder O
Obesity (Silver Spring)
. 2018 Jun;
26(7):1161-1167.
PMID: 29901265
Objective: Obesity in females is often associated with metabolic complications and hyperandrogenism, but the sources of androgens are not completely understood. Therefore, this study investigated whether adipose tissue could be...
5.
Pampanini V, Germani D, Puglianiello A, Stukenborg J, Reda A, Savchuk I, et al.
J Endocrinol
. 2016 Nov;
232(2):247-257.
PMID: 27885054
Prenatal events such as intrauterine growth restriction can affect gonadal development of the offspring and have an impact on reproductive health. To investigate the effects of intrauterine growth restriction induced...
6.
Savchuk I, Morvan M, Soeborg T, Antignac J, Gemzell-Danielsson K, Le Bizec B, et al.
Mol Nutr Food Res
. 2016 Aug;
61(2).
PMID: 27561679
Scope: Resveratrol has a diverse array of healthful effects on metabolic parameters in different experimental paradigms but has also potential to inhibit steroidogenesis in rodent adrenals. The aim of the...
7.
Svechnikov K, Savchuk I, Morvan M, Antignac J, Le Bizec B, Soder O
Horm Res Paediatr
. 2015 Nov;
86(4):253-263.
PMID: 26559938
Humans are significantly exposed to phthalates via food packaging, cosmetics and medical devices such as tubings and catheters. Testicular Leydig cells (LCs) are suggested to be among the main targets...
8.
Savchuk I, Soder O, Svechnikov K
Toxicol Sci
. 2015 Feb;
145(1):149-56.
PMID: 25677926
Numerous studies have reported on testicular toxicity of phthalates in different experimental paradigms and showed that Leydig cells (LCs) were one of the main targets of phthalate actions. Adverse effects...
9.
Savchuk I, Soder O, Svechnikov K
PLoS One
. 2013 Aug;
8(8):e71722.
PMID: 23967237
It is well known that estrogens and estrogen-like endocrine disruptors can suppress steroidogenic gene expression, attenuate androgen production and decrease differentiation of adult Leydig cell lineage. However, there is no...