Isora V Sernandez
Overview
Explore the profile of Isora V Sernandez including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
163
Followers
0
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Recent Articles
1.
Delgado P, Alvarez-Prado A, Marina-Zarate E, Sernandez I, Mur S, de la Barrera J, et al.
PLoS Genet
. 2020 Dec;
16(12):e1008960.
PMID: 33362210
Most B cell lymphomas originate from B cells that have germinal center (GC) experience and bear chromosome translocations and numerous point mutations. GC B cells remodel their immunoglobulin (Ig) genes...
2.
Perez-Garcia A, Perez-Duran P, Wossning T, Sernandez I, Mur S, Canamero M, et al.
EMBO Mol Med
. 2015 Aug;
7(10):1327-36.
PMID: 26282919
Activation-induced deaminase (AID) initiates secondary antibody diversification in germinal center B cells, giving rise to higher affinity antibodies through somatic hypermutation (SHM) or to isotype-switched antibodies through class switch recombination...
3.
Pauklin S, Sernandez I, Bachmann G, Ramiro A, Petersen-Mahrt S
J Exp Med
. 2009 Jan;
206(1):99-111.
PMID: 19139166
The immunological targets of estrogen at the molecular, humoral, and cellular level have been well documented, as has estrogen's role in establishing a gender bias in autoimmunity and cancer. During...
4.
Sernandez I, de Yebenes V, Dorsett Y, Ramiro A
PLoS One
. 2008 Dec;
3(12):e3927.
PMID: 19079594
The humoral immune response critically relies on the secondary diversification of antibodies. This diversification takes places through somatic remodelling of the antibody genes by two molecular mechanisms, Class Switch Recombination...